Web-based digital gene expression atlases for the mouse

Lars Geffers, Bernhard Herrmann, Gregor Eichele

Research output: Contribution to journalReview articlepeer-review

22 Citations (Scopus)

Abstract

Over the past 15 years the publicly available mouse gene expression data determined by in situ hybridization have dramatically increased in scope and spatiotemporal resolution. As a consequence of resources and tools available in the post-genomic era, full transcriptomes in the mouse brain and in the mouse embryo can be studied. Here we introduce and discuss seven current databases (MAMEP, EMBRYS, GenePaint, EURExpress, EuReGene, BGEM, and GENSAT) that grant access to large collections of expression data in mouse. We review the experimental focus, coverage, data assessment, and annotation for each of these databases and the implementation of analytic tools and links to other relevant databases. We provide a user-oriented summary of how to interrogate each database.

Original languageEnglish
Pages (from-to)525-38
Number of pages14
JournalMammalian Genome
Volume23
Issue number9-10
DOIs
Publication statusPublished - Oct 2012
Externally publishedYes

Keywords

  • Animals
  • Atlases as Topic
  • Gene Expression
  • Internet
  • Mice/genetics

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