Urticaria Pigmentosa Without Pruritus

William J Nahm, Denise J Corriveau, Chris A Mathe, W Austin Wyant, Carlos Vega, Anita Arthur, K Chris Min

Research output: Contribution to journalArticleResearchpeer-review


Mastocytosis is a group of disorders characterized by the pathologic accumulation of mast cells in various tissues. One example of mastocytosis is urticaria pigmentosa, which presents with mastocytomas that can cause hives and, when irritated, pruritus. To our knowledge, we are describing the first case of urticaria pigmentosa without pruritus. The patient had a positive Darier's sign, stated that they never felt itchy, and denied ever using a topical steroid or antihistamine. Although our patient declined additional testing, patients like this may benefit from a detailed evaluation of their sensory system through both quantitative sensory testing and genetic analysis. J Drugs Dermatol. 2024;23(3):     doi:10.36849/JDD.7558e.

Original languageEnglish
Pages (from-to)e81-e82
JournalJournal of Drugs in Dermatology
Issue number3
Publication statusPublished - 1 Mar 2024
Externally publishedYes


  • Humans
  • Urticaria Pigmentosa/diagnosis
  • Pruritus/diagnosis
  • Urticaria/diagnosis
  • Mast Cells
  • Emotions


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