Abstract
Contemporary geriatric research focuses mainly on observational clinical studies and epidemiological surveys and the translation of basic scientific results from biogerontology into a clinical context is often neglected. Following a definition of translational research the article gives an overview of recent key publications in experimental biogerontology with a special emphasis on their relevance for clinical geriatrics. The topics dealt with include age-induced loss of skeletal muscle (sarcopenia), the aging immune system (immunosenescence) and neurodegenerative disorders (Alzheimer's and Parkinson's disease).
Translated title of the contribution | Translational research in geriatrics?: A plea based on current biomedical key publications |
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Original language | German |
Pages (from-to) | 569-576 |
Number of pages | 8 |
Journal | Zeitschrift fur Gerontologie und Geriatrie |
Volume | 46 |
Issue number | 6 |
DOIs | |
Publication status | Published - Aug 2013 |
Externally published | Yes |
Keywords
- Alzheimer disease
- Immunosenescence
- Parkinson disease
- Sarcopenia
- Translational research