Therapeutic efficacy of clindamycin in combination with quinine for treating uncomplicated malaria in a village dispensary in Gabon

Michel Vaillant; Pascal Millet; Adrian Luty; Paul Tshopamba; Faustin Lekoulou; Justice Mayombo; Alain J. Georges; Philippe Deloron

doi:10.1046/j.1365-3156.1997.d01-411.x

Therapeutic efficacy of clindamycin in combination with quinine for treating uncomplicated malaria in a village dispensary in Gabon

Michel Vaillant, Pascal Millet, Adrian Luty, Paul Tshopamba, Faustin Lekoulou, Justice Mayombo, Alain J. Georges, Philippe Deloron^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

20 Citations (Scopus)

Abstract

The efficacy of a 3-day clindamycin-quinine regimen to treat clinical malaria attacks was investigated in 256 children from western Gabon. Treatment was well tolerated by all of the children and its efficacy was higher than 97% by day 20. Thus this 3-day clindamycin-quinine regimen might constitute a potential alternative to chloroquine for treating clinical malarial attacks in children from Gabon.

Original language	English
Pages (from-to)	917-919
Number of pages	3
Journal	Tropical Medicine and International Health
Volume	2
Issue number	9
DOIs	https://doi.org/10.1046/j.1365-3156.1997.d01-411.x
Publication status	Published - 1997
Externally published	Yes

Keywords

Clindamycin
Gabon
Malaria
Plasmodium falciparum
Quinine

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10.1046/j.1365-3156.1997.d01-411.x

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abstract = "The efficacy of a 3-day clindamycin-quinine regimen to treat clinical malaria attacks was investigated in 256 children from western Gabon. Treatment was well tolerated by all of the children and its efficacy was higher than 97% by day 20. Thus this 3-day clindamycin-quinine regimen might constitute a potential alternative to chloroquine for treating clinical malarial attacks in children from Gabon.",

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AU - Vaillant, Michel

AU - Millet, Pascal

AU - Luty, Adrian

AU - Tshopamba, Paul

AU - Lekoulou, Faustin

AU - Mayombo, Justice

AU - Georges, Alain J.

AU - Deloron, Philippe

PY - 1997

Y1 - 1997

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AB - The efficacy of a 3-day clindamycin-quinine regimen to treat clinical malaria attacks was investigated in 256 children from western Gabon. Treatment was well tolerated by all of the children and its efficacy was higher than 97% by day 20. Thus this 3-day clindamycin-quinine regimen might constitute a potential alternative to chloroquine for treating clinical malarial attacks in children from Gabon.

KW - Clindamycin

KW - Gabon

KW - Malaria

KW - Plasmodium falciparum

KW - Quinine

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U2 - 10.1046/j.1365-3156.1997.d01-411.x

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JF - Tropical Medicine and International Health

IS - 9

ER -

Therapeutic efficacy of clindamycin in combination with quinine for treating uncomplicated malaria in a village dispensary in Gabon

Abstract

Keywords

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