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The Modulatory Effects of DMF on Microglia in Aged Mice Are Sex-Specific
Virginia Mela
, Aline Sayd Gaban
, Eoin O’neill
,
Sibylle Bechet
, Aífe Walsh
, Marina A. Lynch
*
*
Corresponding author for this work
Research output
:
Contribution to journal
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Article
›
Research
›
peer-review
14
Citations (Scopus)
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Keyphrases
Microglia
100%
Sex-specific
100%
Dimethyl Fumarate
100%
Aged Mice
100%
Modulatory Effect
100%
Neurodegenerative Diseases
40%
Female Mice
40%
Male Mice
40%
Glycolysis
40%
Sex Effect
40%
Microglial Metabolism
40%
Sex-related Differences
40%
Antioxidant
20%
Cell Metabolism
20%
Inflammation
20%
Microglial Activation
20%
Activation State
20%
Adulthood
20%
Young Males
20%
Young Female
20%
Rodents
20%
Inflammatory Mediators
20%
Mechanism of Action
20%
Alzheimer's Disease Model
20%
Glyceraldehyde-3-phosphate Dehydrogenase
20%
Microglia Phenotype
20%
Reduced Function
20%
Early Postnatal Period
20%
Relapsing-remitting multiple Sclerosis
20%
Fumaric Acid Esters
20%
Psoriasis Treatment
20%
Pharmacology, Toxicology and Pharmaceutical Science
Fumaric Acid Dimethyl Ester
100%
Degenerative Disease
66%
Anti-Inflammatory Drug
33%
Glyceraldehyde 3 Phosphate Dehydrogenase
33%
Prevalence
33%
Alzheimer's Disease
33%
Inflammation
33%
Multiple Sclerosis
33%
Antioxidant
33%
Psoriasis
33%
Fumaric Acid
33%
Neuroscience
Microglia
100%
Metabolic Pathway
75%
Neurodegenerative Disorder
50%
Glycolysis
50%
Anti-Inflammatory
25%
Antioxidant
25%
Relapsing Remitting Multiple Sclerosis
25%
Alzheimer's Disease
25%
Glyceraldehyde 3 Phosphate Dehydrogenase
25%
Biochemistry, Genetics and Molecular Biology
Microglia
100%
Metabolic Pathway
50%
Glycolysis
50%
Prevalence
25%
Cell Metabolism
25%
Mediator
25%
Glyceraldehyde 3-Phosphate Dehydrogenase
25%
Fumaric Acid
25%
Anti-Inflammatory
25%
Sex Differences
25%