The Inflammatory Skin Disease map: an interactive computational resource focused on molecular mechanisms in psoriasis and atopic dermatitis

Marcio L. Acencio; Oxana Lopata; Ahmed A. Hemedan; Nick Dand; Stephan Weidinger; Lavinia Paternoster; Sara J. Brown; Joseph Rastrick; Catherine H. Smith; Matthias Hübenthal; Ravi Ramessur; Matladi Ndlovu; Soumyabrata Ghosh; Xinhui Wang; Reinhard Schneider; Venkata Satagopam; Marek Ostaszewski

doi:10.1093/bjd/ljaf491

The Inflammatory Skin Disease map: an interactive computational resource focused on molecular mechanisms in psoriasis and atopic dermatitis

Marcio L. Acencio
, Oxana Lopata
, Ahmed A. Hemedan
, Nick Dand
, Stephan Weidinger
, Lavinia Paternoster
, Sara J. Brown
, Joseph Rastrick
, Catherine H. Smith
, Matthias Hübenthal
, Ravi Ramessur
, Matladi Ndlovu
, Soumyabrata Ghosh
, Xinhui Wang
, Reinhard Schneider
, Venkata Satagopam
, Marek Ostaszewski^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

Abstract

In this research letter, we introduce the Inflammatory Skin Diseases (ISD) map, a visual and computational representation of a molecular interaction network of molecular mechanisms of atopic dermatitis (AD) and psoriasis (PsO) (https://disease-maps.io/isd/). This knowledge repository can be used as a graphical review, to visualize complex omics data, or as a simulation testbed for research hypotheses. The purpose of the ISD map is to represent key molecular mechanisms of AD and PsO, facilitating information search and data interpretation, and supporting computational analyses.

Original language	English
Pages (from-to)	597-599
Number of pages	3
Journal	British Journal of Dermatology
Volume	194
Issue number	3
DOIs	https://doi.org/10.1093/bjd/ljaf491
Publication status	Published - 18 Feb 2026
Externally published	Yes

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Acencio, M. L., Lopata, O., Hemedan, A. A., Dand, N., Weidinger, S., Paternoster, L., Brown, S. J., Rastrick, J., Smith, C. H., Hübenthal, M., Ramessur, R., Ndlovu, M., Ghosh, S., Wang, X., Schneider, R., Satagopam, V., & Ostaszewski, M. (2026). The Inflammatory Skin Disease map: an interactive computational resource focused on molecular mechanisms in psoriasis and atopic dermatitis. British Journal of Dermatology, 194(3), 597-599. https://doi.org/10.1093/bjd/ljaf491

@article{dc59795155544076b9592e111dbd4fdd,

title = "The Inflammatory Skin Disease map: an interactive computational resource focused on molecular mechanisms in psoriasis and atopic dermatitis",

abstract = "In this research letter, we introduce the Inflammatory Skin Diseases (ISD) map, a visual and computational representation of a molecular interaction network of molecular mechanisms of atopic dermatitis (AD) and psoriasis (PsO) (https://disease-maps.io/isd/). This knowledge repository can be used as a graphical review, to visualize complex omics data, or as a simulation testbed for research hypotheses. The purpose of the ISD map is to represent key molecular mechanisms of AD and PsO, facilitating information search and data interpretation, and supporting computational analyses.",

author = "Acencio, \{Marcio L.\} and Oxana Lopata and Hemedan, \{Ahmed A.\} and Nick Dand and Stephan Weidinger and Lavinia Paternoster and Brown, \{Sara J.\} and Joseph Rastrick and Smith, \{Catherine H.\} and Matthias H{\"u}benthal and Ravi Ramessur and Matladi Ndlovu and Soumyabrata Ghosh and Xinhui Wang and Reinhard Schneider and Venkata Satagopam and Marek Ostaszewski",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2025. Published by Oxford University Press on behalf of British Association of Dermatologists.",

year = "2026",

month = feb,

day = "18",

doi = "10.1093/bjd/ljaf491",

language = "English",

volume = "194",

pages = "597--599",

journal = "British Journal of Dermatology",

issn = "0007-0963",

publisher = "Oxford University Press",

number = "3",

}

Acencio, ML, Lopata, O, Hemedan, AA, Dand, N, Weidinger, S, Paternoster, L, Brown, SJ, Rastrick, J, Smith, CH, Hübenthal, M, Ramessur, R, Ndlovu, M, Ghosh, S, Wang, X, Schneider, R, Satagopam, V & Ostaszewski, M 2026, 'The Inflammatory Skin Disease map: an interactive computational resource focused on molecular mechanisms in psoriasis and atopic dermatitis', British Journal of Dermatology, vol. 194, no. 3, pp. 597-599. https://doi.org/10.1093/bjd/ljaf491

TY - JOUR

T1 - The Inflammatory Skin Disease map

T2 - an interactive computational resource focused on molecular mechanisms in psoriasis and atopic dermatitis

AU - Acencio, Marcio L.

AU - Lopata, Oxana

AU - Hemedan, Ahmed A.

AU - Dand, Nick

AU - Weidinger, Stephan

AU - Paternoster, Lavinia

AU - Brown, Sara J.

AU - Rastrick, Joseph

AU - Smith, Catherine H.

AU - Hübenthal, Matthias

AU - Ramessur, Ravi

AU - Ndlovu, Matladi

AU - Ghosh, Soumyabrata

AU - Wang, Xinhui

AU - Schneider, Reinhard

AU - Satagopam, Venkata

AU - Ostaszewski, Marek

PY - 2026/2/18

Y1 - 2026/2/18

N2 - In this research letter, we introduce the Inflammatory Skin Diseases (ISD) map, a visual and computational representation of a molecular interaction network of molecular mechanisms of atopic dermatitis (AD) and psoriasis (PsO) (https://disease-maps.io/isd/). This knowledge repository can be used as a graphical review, to visualize complex omics data, or as a simulation testbed for research hypotheses. The purpose of the ISD map is to represent key molecular mechanisms of AD and PsO, facilitating information search and data interpretation, and supporting computational analyses.

AB - In this research letter, we introduce the Inflammatory Skin Diseases (ISD) map, a visual and computational representation of a molecular interaction network of molecular mechanisms of atopic dermatitis (AD) and psoriasis (PsO) (https://disease-maps.io/isd/). This knowledge repository can be used as a graphical review, to visualize complex omics data, or as a simulation testbed for research hypotheses. The purpose of the ISD map is to represent key molecular mechanisms of AD and PsO, facilitating information search and data interpretation, and supporting computational analyses.

UR - https://www.scopus.com/pages/publications/105030520847

U2 - 10.1093/bjd/ljaf491

DO - 10.1093/bjd/ljaf491

M3 - Article

C2 - 41329629

AN - SCOPUS:105030520847

SN - 0007-0963

VL - 194

SP - 597

EP - 599

JO - British Journal of Dermatology

JF - British Journal of Dermatology

IS - 3

ER -

The Inflammatory Skin Disease map: an interactive computational resource focused on molecular mechanisms in psoriasis and atopic dermatitis

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