The graphical representation of clinical trials with particular reference to measurements over time

S. J. Senn*, P. Auclair, Samuel Johnson

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Abstract

Clinical trials are frequently analysed as if they were surveys when they are in fact experiments. In particular the experimental basis of clinical trials is rarely reflected in the graphs which are used to illustrate them. Proposals are made, and illustrated by example, as to how appropriate figures may be devised, both for parallel‐group designs and for crossover trials, to illustrate the experimental nature of clinical trials with measurements over time. It is incident to physicians, I am afraid, beyond all men, to mistake subsequence for consequence.

Original languageEnglish
Pages (from-to)1287-1302
Number of pages16
JournalStatistics in Medicine
Volume9
Issue number11
DOIs
Publication statusPublished - Nov 1990
Externally publishedYes

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