The central biobank and virtual biobank of BIOMARKAPD: a resource for studies on neurodegenerative diseases

B. L. Reijs; C. E. Teunissen; N. Goncharenko; F. Betsou; K. Blennow; I. Baldeiras; F. Brosseron; E. Cavedo; T. Fladby; L. Froelich; T. Gabryelewicz; H. Gurvit; E. Kapaki; P. Koson; L. Kulic; S. Lehmann; P. Lewczuk; A. Lleo; W. Maetzler; A. de Mendonca; A. M. Miller; J. L. Molinuevo; B. Mollenhauer; L. Parnetti; U. Rot; A. Schneider; A. H. Simonsen; F. Tagliavini; M. Tsolaki; M. M. Verbeek; F. R. Verhey; M. Zboch; B. Winblad; P. Scheltens; H. Zetterberg; P. J. Visser

doi:10.26481/dis.20180221br

The central biobank and virtual biobank of BIOMARKAPD: a resource for studies on neurodegenerative diseases

B. L. Reijs, C. E. Teunissen, N. Goncharenko, F. Betsou, K. Blennow, I. Baldeiras, F. Brosseron, E. Cavedo, T. Fladby, L. Froelich, T. Gabryelewicz, H. Gurvit, E. Kapaki, P. Koson, L. Kulic, S. Lehmann, P. Lewczuk, A. Lleo, W. Maetzler, A. de MendoncaA. M. Miller, J. L. Molinuevo, B. Mollenhauer, L. Parnetti, U. Rot, A. Schneider, A. H. Simonsen, F. Tagliavini, M. Tsolaki, M. M. Verbeek, F. R. Verhey, M. Zboch, B. Winblad, P. Scheltens, H. Zetterberg, P. J. Visser

Biospecimen Research Group

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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Abstract

Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's Disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme - Neurodegenerative Disease Research (JPND), that aims to improve the clinical use of body fluid markers for the diagnosis and prognosis of Alzheimer’s disease (AD) and Parkinson’s disease (PD). The objective was to standardize the assessment of existing assays and to validate novel fluid biomarkers for AD and PD. To support the validation of novel biomarkers and assays, a central and a virtual biobank for body fluids and associated data from subjects with neurodegenerative diseases have been established. In the central biobank, cerebrospinal fluid (CSF) and blood samples were collected according to the BIOMARKAPD standardized preanalytical procedures (SOP) and stored at Integrated BioBank of Luxembourg (IBBL). The virtual biobank provides an overview of available CSF, plasma, serum, and DNA samples at each site. Currently, at the central biobank of BIOMARKAPD samples are available from over 400 subjects with normal cognition, mild cognitive impairment (MCI), AD, frontotemporal dementia (FTD), vascular dementia (VaD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), PD, PD with dementia, and dementia with Lewy bodies (DLB). The virtual biobank contains information on over 8600 subjects with varying diagnoses from 21 local biobanks. A website has been launched to enable sample requests from the central biobank and virtual biobank.

Original language	English
Title of host publication	Cognitive correlates of cerebrospinal fluid biomarkers for alzheimer’s disease
Place of Publication	Maastricht
Publisher	Ridderprint
Chapter	7
Pages	120-132
Number of pages	13
ISBN (Print)	978-94-6299-841-4
DOIs	https://doi.org/10.26481/dis.20180221br
Publication status	Published - 21 Feb 2018

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Reijs, B. L., Teunissen, C. E., Goncharenko, N., Betsou, F., Blennow, K., Baldeiras, I., Brosseron, F., Cavedo, E., Fladby, T., Froelich, L., Gabryelewicz, T., Gurvit, H., Kapaki, E., Koson, P., Kulic, L., Lehmann, S., Lewczuk, P., Lleo, A., Maetzler, W., ... Visser, P. J. (2018). The central biobank and virtual biobank of BIOMARKAPD: a resource for studies on neurodegenerative diseases. In Cognitive correlates of cerebrospinal fluid biomarkers for alzheimer’s disease (pp. 120-132). Ridderprint. https://doi.org/10.26481/dis.20180221br

@inbook{3fcfe4cb69794b6e927cd1550240bda1,

title = "The central biobank and virtual biobank of BIOMARKAPD: a resource for studies on neurodegenerative diseases",

abstract = "Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's Disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme - Neurodegenerative Disease Research (JPND), that aims to improve the clinical use of body fluid markers for the diagnosis and prognosis of Alzheimer{\textquoteright}s disease (AD) and Parkinson{\textquoteright}s disease (PD). The objective was to standardize the assessment of existing assays and to validate novel fluid biomarkers for AD and PD. To support the validation of novel biomarkers and assays, a central and a virtual biobank for body fluids and associated data from subjects with neurodegenerative diseases have been established. In the central biobank, cerebrospinal fluid (CSF) and blood samples were collected according to the BIOMARKAPD standardized preanalytical procedures (SOP) and stored at Integrated BioBank of Luxembourg (IBBL). The virtual biobank provides an overview of available CSF, plasma, serum, and DNA samples at each site. Currently, at the central biobank of BIOMARKAPD samples are available from over 400 subjects with normal cognition, mild cognitive impairment (MCI), AD, frontotemporal dementia (FTD), vascular dementia (VaD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), PD, PD with dementia, and dementia with Lewy bodies (DLB). The virtual biobank contains information on over 8600 subjects with varying diagnoses from 21 local biobanks. A website has been launched to enable sample requests from the central biobank and virtual biobank.",

author = "Reijs, {B. L.} and Teunissen, {C. E.} and N. Goncharenko and F. Betsou and K. Blennow and I. Baldeiras and F. Brosseron and E. Cavedo and T. Fladby and L. Froelich and T. Gabryelewicz and H. Gurvit and E. Kapaki and P. Koson and L. Kulic and S. Lehmann and P. Lewczuk and A. Lleo and W. Maetzler and {de Mendonca}, A. and Miller, {A. M.} and Molinuevo, {J. L.} and B. Mollenhauer and L. Parnetti and U. Rot and A. Schneider and Simonsen, {A. H.} and F. Tagliavini and M. Tsolaki and Verbeek, {M. M.} and Verhey, {F. R.} and M. Zboch and B. Winblad and P. Scheltens and H. Zetterberg and Visser, {P. J.}",

note = "Cognitive correlates of cerebrospinal fluid biomarkers for alzheimer{\textquoteright}s disease Award date: 21 Feb 2018 2018 , chapter 7, p.81-132 (already Published in: Frontiers Neurology 2015;6:216) Chapter published in Doctoral Thesis Research output: Internal › Doctoral Thesis",

year = "2018",

month = feb,

day = "21",

doi = "10.26481/dis.20180221br",

language = "English",

isbn = "978-94-6299-841-4",

pages = "120--132",

booktitle = "Cognitive correlates of cerebrospinal fluid biomarkers for alzheimer{\textquoteright}s disease",

publisher = "Ridderprint",

}

Reijs, BL, Teunissen, CE, Goncharenko, N, Betsou, F, Blennow, K, Baldeiras, I, Brosseron, F, Cavedo, E, Fladby, T, Froelich, L, Gabryelewicz, T, Gurvit, H, Kapaki, E, Koson, P, Kulic, L, Lehmann, S, Lewczuk, P, Lleo, A, Maetzler, W, de Mendonca, A, Miller, AM, Molinuevo, JL, Mollenhauer, B, Parnetti, L, Rot, U, Schneider, A, Simonsen, AH, Tagliavini, F, Tsolaki, M, Verbeek, MM, Verhey, FR, Zboch, M, Winblad, B, Scheltens, P, Zetterberg, H & Visser, PJ 2018, The central biobank and virtual biobank of BIOMARKAPD: a resource for studies on neurodegenerative diseases. in Cognitive correlates of cerebrospinal fluid biomarkers for alzheimer’s disease. Ridderprint, Maastricht, pp. 120-132. https://doi.org/10.26481/dis.20180221br

The central biobank and virtual biobank of BIOMARKAPD: a resource for studies on neurodegenerative diseases. / Reijs, B. L.; Teunissen, C. E.; Goncharenko, N. et al.
Cognitive correlates of cerebrospinal fluid biomarkers for alzheimer’s disease. Maastricht: Ridderprint, 2018. p. 120-132.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - The central biobank and virtual biobank of BIOMARKAPD: a resource for studies on neurodegenerative diseases

AU - Reijs, B. L.

AU - Teunissen, C. E.

AU - Goncharenko, N.

AU - Betsou, F.

AU - Blennow, K.

AU - Baldeiras, I.

AU - Brosseron, F.

AU - Cavedo, E.

AU - Fladby, T.

AU - Froelich, L.

AU - Gabryelewicz, T.

AU - Gurvit, H.

AU - Kapaki, E.

AU - Koson, P.

AU - Kulic, L.

AU - Lehmann, S.

AU - Lewczuk, P.

AU - Lleo, A.

AU - Maetzler, W.

AU - de Mendonca, A.

AU - Miller, A. M.

AU - Molinuevo, J. L.

AU - Mollenhauer, B.

AU - Parnetti, L.

AU - Rot, U.

AU - Schneider, A.

AU - Simonsen, A. H.

AU - Tagliavini, F.

AU - Tsolaki, M.

AU - Verbeek, M. M.

AU - Verhey, F. R.

AU - Zboch, M.

AU - Winblad, B.

AU - Scheltens, P.

AU - Zetterberg, H.

AU - Visser, P. J.

N1 - Cognitive correlates of cerebrospinal fluid biomarkers for alzheimer’s disease Award date: 21 Feb 2018 2018 , chapter 7, p.81-132 (already Published in: Frontiers Neurology 2015;6:216) Chapter published in Doctoral Thesis Research output: Internal › Doctoral Thesis

PY - 2018/2/21

Y1 - 2018/2/21

N2 - Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's Disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme - Neurodegenerative Disease Research (JPND), that aims to improve the clinical use of body fluid markers for the diagnosis and prognosis of Alzheimer’s disease (AD) and Parkinson’s disease (PD). The objective was to standardize the assessment of existing assays and to validate novel fluid biomarkers for AD and PD. To support the validation of novel biomarkers and assays, a central and a virtual biobank for body fluids and associated data from subjects with neurodegenerative diseases have been established. In the central biobank, cerebrospinal fluid (CSF) and blood samples were collected according to the BIOMARKAPD standardized preanalytical procedures (SOP) and stored at Integrated BioBank of Luxembourg (IBBL). The virtual biobank provides an overview of available CSF, plasma, serum, and DNA samples at each site. Currently, at the central biobank of BIOMARKAPD samples are available from over 400 subjects with normal cognition, mild cognitive impairment (MCI), AD, frontotemporal dementia (FTD), vascular dementia (VaD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), PD, PD with dementia, and dementia with Lewy bodies (DLB). The virtual biobank contains information on over 8600 subjects with varying diagnoses from 21 local biobanks. A website has been launched to enable sample requests from the central biobank and virtual biobank.

AB - Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's Disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme - Neurodegenerative Disease Research (JPND), that aims to improve the clinical use of body fluid markers for the diagnosis and prognosis of Alzheimer’s disease (AD) and Parkinson’s disease (PD). The objective was to standardize the assessment of existing assays and to validate novel fluid biomarkers for AD and PD. To support the validation of novel biomarkers and assays, a central and a virtual biobank for body fluids and associated data from subjects with neurodegenerative diseases have been established. In the central biobank, cerebrospinal fluid (CSF) and blood samples were collected according to the BIOMARKAPD standardized preanalytical procedures (SOP) and stored at Integrated BioBank of Luxembourg (IBBL). The virtual biobank provides an overview of available CSF, plasma, serum, and DNA samples at each site. Currently, at the central biobank of BIOMARKAPD samples are available from over 400 subjects with normal cognition, mild cognitive impairment (MCI), AD, frontotemporal dementia (FTD), vascular dementia (VaD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), PD, PD with dementia, and dementia with Lewy bodies (DLB). The virtual biobank contains information on over 8600 subjects with varying diagnoses from 21 local biobanks. A website has been launched to enable sample requests from the central biobank and virtual biobank.

U2 - 10.26481/dis.20180221br

DO - 10.26481/dis.20180221br

M3 - Chapter

SN - 978-94-6299-841-4

SP - 120

EP - 132

BT - Cognitive correlates of cerebrospinal fluid biomarkers for alzheimer’s disease

PB - Ridderprint

CY - Maastricht

ER -

The central biobank and virtual biobank of BIOMARKAPD: a resource for studies on neurodegenerative diseases

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