TY - JOUR
T1 - The association between colorectal cancer and index of nutritional quality (INQ); a case-control study
AU - Gholamalizadeh, Maryam
AU - Shekari, Soheila
AU - Hassanpour Ardekanizadeh, Naeemeh
AU - Vahid, Farhad
AU - Aslani, Zahra
AU - Akbari, Mohammad Esmail
AU - Alemrajabi, Mahdi
AU - Lavasani, Ali
AU - Hajipour, Azadeh
AU - Hosseinzadeh, Payam
AU - Asbaghi, Omid
AU - Doaei, Saeid
N1 - Funding Information:
Declared conflict of interest of all authors: none Disclosure of funding: Funding for this study was provided by Shahid Beheshti University of Medical Sciences, Tehran, Iran (Code: 43006535). Corresponding authors: Saeid Doaei: [email protected] Omid Asbaghi: [email protected]
Publisher Copyright:
© 2023, IBEPEGE - Inst. Bras. Estudos Pesquisas Gastroent.. All rights reserved.
PY - 2023/4
Y1 - 2023/4
N2 - Background – The nutritional quality of diet may influence the risk of colorectal cancer (CRC). This study compared the Index of Nutritional Quality (INQ) of various dietary components between colo-rectal cancer patients and healthy controls. Methods – A total of 480 participants were enrolled in the study (160 patients with colorectal cancer as a case group and 320 healthy control). An analysis was conducted on the general characteristics of the participants, their medical histories, anthropometric indicators, physical activity, alcohol consumption, reproductive history, smoking and food intake. A valid food frequency questionnaire was used to assess nutrient intake and INQ was calculated from daily nutrient intake. Results – A Significant inverse association was found between CRC and INQ for vitamins A (OR=0.01, CI: 0.01–0.01), K (OR=0.04, CI: 0.01–0.15), and B12 (OR=0.71, CI: 0.51–0.98), B5 (OR=0.43, CI: 0.00–0.01), zinc (OR=0.35, CI: 0.13–0.95), and phosphorus (OR=0.17, 0.19–0.94). The association between the INQ of vitamin B12 and zinc with colorectal cancer was disappeared after age adjustment. There was a significant negative association between CRC with the INQ of vitamins A, K, B5, phosphorus, and calcium after further adjustments for gender, BMI, menopausal status, and total energy intake. Conclusion – CRC is significantly associated with INQ for some micronutrients. INQ can be considered as an indicator to assess clinical nutritional problems.
AB - Background – The nutritional quality of diet may influence the risk of colorectal cancer (CRC). This study compared the Index of Nutritional Quality (INQ) of various dietary components between colo-rectal cancer patients and healthy controls. Methods – A total of 480 participants were enrolled in the study (160 patients with colorectal cancer as a case group and 320 healthy control). An analysis was conducted on the general characteristics of the participants, their medical histories, anthropometric indicators, physical activity, alcohol consumption, reproductive history, smoking and food intake. A valid food frequency questionnaire was used to assess nutrient intake and INQ was calculated from daily nutrient intake. Results – A Significant inverse association was found between CRC and INQ for vitamins A (OR=0.01, CI: 0.01–0.01), K (OR=0.04, CI: 0.01–0.15), and B12 (OR=0.71, CI: 0.51–0.98), B5 (OR=0.43, CI: 0.00–0.01), zinc (OR=0.35, CI: 0.13–0.95), and phosphorus (OR=0.17, 0.19–0.94). The association between the INQ of vitamin B12 and zinc with colorectal cancer was disappeared after age adjustment. There was a significant negative association between CRC with the INQ of vitamins A, K, B5, phosphorus, and calcium after further adjustments for gender, BMI, menopausal status, and total energy intake. Conclusion – CRC is significantly associated with INQ for some micronutrients. INQ can be considered as an indicator to assess clinical nutritional problems.
KW - Colorectal cancer
KW - dietary intake
KW - the Index of Nutritional Quality
UR - http://www.scopus.com/inward/record.url?scp=85167395321&partnerID=8YFLogxK
UR - https://pubmed.ncbi.nlm.nih.gov/37556748
U2 - 10.1590/S0004-2803.20230222-169
DO - 10.1590/S0004-2803.20230222-169
M3 - Article
C2 - 37556748
AN - SCOPUS:85167395321
SN - 0004-2803
VL - 60
SP - 217
EP - 223
JO - Arquivos de Gastroenterologia
JF - Arquivos de Gastroenterologia
IS - 2
ER -