@article{8d94e3c915fa422abd40d1193ed0eb03,
title = "Swine influenza virus antibodies in humans, Western Europe, 2009",
abstract = "Serologic studies for swine infl uenza viruses (SIVs) in humans with occupational exposure to swine have been reported from Americas not from Europe. We compared levels of neutralizing antibodies against 3 infl uenza viruses – pandemic (H1N1) 2009, an avian-like enzootic subtype H1N1 SIV, and a 2007-08 seasonal subtype H1N1 – in 211 persons with swine contact and 224 matched controls in Luxembourg. Persons whose profession involved contact with swine had more neutralizing antibodies against SIV and pandemic (H1N1) 2009 virus than did the controls. Controls also had antibodies against these viruses although exposure to them was unlikely. Antibodies against SIV and pandemic (H1N1) 2009 virus correlated with each other but not with seasonal subtype H1N1 virus. Sequential exposure to variants of seasonal infl uenza (H1N1) viruses may have increased chances for serologic cross-reactivity with antigenically distinct viruses. Further studies are needed to determine the extent to which serologic responses correlate with infection.",
author = "Gerloff, {Nancy A.} and Kremer, {Jacques R.} and Emilie Charpentier and Aur{\'e}lie Sausy and Olinger, {Christophe M.} and Pierre Weicherding and John Schuh and {Van Reeth}, Kristien and Muller, {Claude P.}",
note = "Funding Information: We thank Constant Muellesch and Gerard Heitz for assistance in recruiting study participants and Joel Mossong for his scientific expertise. This research was supported by the Ministry of Health. N.A.G. received funding from the “Fonds National de la Recherche” of the Ministry of Research of the Grand-Duchy of Luxembourg. Dr. Gerloff is a molecular biologist and virolo-gist at the Institute of Immunology Centre de Re-cherche Public de la Sante/Laboratoire National de Sante in Luxembourg. Her main research interest is molecular epidemiology of infectious diseases, es-pecially influenza and other respiratory viruses. Funding Information: This research was supported by the Ministry of Health. N.A.G. received funding from the “Fonds National de la Recherche” of the Ministry of Research of the Grand-Duchy of Luxembourg. Publisher Copyright: {\textcopyright} 2011, Amaltea Medical Publishing House. All rights reserved.",
year = "2011",
language = "English",
volume = "14",
pages = "10--18",
journal = "Romanian Journal of Infectious Diseases",
issn = "1454-3389",
publisher = "Amaltea Medical Publishing House",
number = "1",
}