Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates

Benjamin Solomon; Enriqueta Felip; Jair Bar; Guy Berchem; Lyudmila Bazhenova; Pierre Saintigny; Nicolas Girard; Raed Sulaiman; Catherine Bresson; Fanny Wunder; J. Jack Lee; Jacques Raynaud; Eitan Rubin; Brandon Young; Vladimir Lazar; Amir Onn; Brian Leyland Jones; Razelle Kurzrock

doi:10.1158/1538-7445.AM2019-CT223

Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates

Benjamin Solomon
, Enriqueta Felip
, Jair Bar
, Guy Berchem
, Lyudmila Bazhenova
, Pierre Saintigny
, Nicolas Girard
, Raed Sulaiman
, Catherine Bresson
, Fanny Wunder
, J. Jack Lee
, Jacques Raynaud
, Eitan Rubin
, Brandon Young
, Vladimir Lazar
, Amir Onn
, Brian Leyland Jones
, Razelle Kurzrock

Luxembourg Institute of Health

Research output: Contribution to journal › Meeting Abstract › peer-review

Original language	English
Article number	CT223
Journal	Cancer Research
Volume	79
Issue number	13 Suppl.
DOIs	https://doi.org/10.1158/1538-7445.AM2019-CT223
Publication status	Published - Jul 2019
Event	Annual Meeting of the American Association for Cancer Research (AACR) 2019 - Atlanta, United States Duration: 29 Mar 2019 → 3 Apr 2019

Access to Document

10.1158/1538-7445.AM2019-CT223

Cite this

Solomon, B., Felip, E., Bar, J., Berchem, G., Bazhenova, L., Saintigny, P., Girard, N., Sulaiman, R., Bresson, C., Wunder, F., Lee, J. J., Raynaud, J., Rubin, E., Young, B., Lazar, V., Onn, A., Jones, B. L., & Kurzrock, R. (2019). Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates. Cancer Research, 79(13 Suppl.), Article CT223. https://doi.org/10.1158/1538-7445.AM2019-CT223

Solomon, Benjamin ; Felip, Enriqueta ; Bar, Jair et al. / Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates. In: Cancer Research. 2019 ; Vol. 79, No. 13 Suppl.

@article{c8a3a6f70bb64e0e8ee8fdab99173fe5,

title = "Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates",

author = "Benjamin Solomon and Enriqueta Felip and Jair Bar and Guy Berchem and Lyudmila Bazhenova and Pierre Saintigny and Nicolas Girard and Raed Sulaiman and Catherine Bresson and Fanny Wunder and Lee, \{J. Jack\} and Jacques Raynaud and Eitan Rubin and Brandon Young and Vladimir Lazar and Amir Onn and Jones, \{Brian Leyland\} and Razelle Kurzrock",

year = "2019",

month = jul,

doi = "10.1158/1538-7445.AM2019-CT223",

language = "English",

volume = "79",

journal = "Cancer Research",

issn = "0008-5472",

publisher = "American Association for Cancer Research Inc.",

number = "13 Suppl.",

note = "Annual Meeting of the American Association for Cancer Research (AACR) 2019 ; Conference date: 29-03-2019 Through 03-04-2019",

}

Solomon, B, Felip, E, Bar, J, Berchem, G, Bazhenova, L, Saintigny, P, Girard, N, Sulaiman, R, Bresson, C, Wunder, F, Lee, JJ, Raynaud, J, Rubin, E, Young, B, Lazar, V, Onn, A, Jones, BL & Kurzrock, R 2019, 'Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates', Cancer Research, vol. 79, no. 13 Suppl., CT223. https://doi.org/10.1158/1538-7445.AM2019-CT223

Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates. / Solomon, Benjamin; Felip, Enriqueta; Bar, Jair et al.
In: Cancer Research, Vol. 79, No. 13 Suppl., CT223, 07.2019.

Research output: Contribution to journal › Meeting Abstract › peer-review

TY - JOUR

T1 - Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates

AU - Solomon, Benjamin

AU - Felip, Enriqueta

AU - Bar, Jair

AU - Berchem, Guy

AU - Bazhenova, Lyudmila

AU - Saintigny, Pierre

AU - Girard, Nicolas

AU - Sulaiman, Raed

AU - Bresson, Catherine

AU - Wunder, Fanny

AU - Lee, J. Jack

AU - Raynaud, Jacques

AU - Rubin, Eitan

AU - Young, Brandon

AU - Lazar, Vladimir

AU - Onn, Amir

AU - Jones, Brian Leyland

AU - Kurzrock, Razelle

PY - 2019/7

Y1 - 2019/7

U2 - 10.1158/1538-7445.AM2019-CT223

DO - 10.1158/1538-7445.AM2019-CT223

M3 - Meeting Abstract

SN - 0008-5472

VL - 79

JO - Cancer Research

JF - Cancer Research

IS - 13 Suppl.

M1 - CT223

T2 - Annual Meeting of the American Association for Cancer Research (AACR) 2019

Y2 - 29 March 2019 through 3 April 2019

ER -

Solomon B, Felip E, Bar J, Berchem G, Bazhenova L, Saintigny P et al. Survival Prolongation by Rationale INnovative Genomics (SPRING): An international WIN Consortium Phase I/II proof-of-concept study to explore the safety and efficacy of a tri-therapy approach using avelumab, palbociclib and axitinib in advanced/metastatic non-small cell lung cancer (NSCLC) with integrated genomic and transcriptomic correlates. Cancer Research. 2019 Jul;79(13 Suppl.): CT223. doi: 10.1158/1538-7445.AM2019-CT223