Statistical issues in short-term trials in asthma

Stephen John Senn

doi:10.1177/009286159302700321

Statistical issues in short-term trials in asthma

Stephen John Senn^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Abstract

Some current practices in designing and analyzing short-term trials in asthma are examined from a statistical point of view. The trials considered consist principally of crossover trials to examine dose response, onset of action, duration of action, and protective effects of treatments or bioequivalence. It is concluded that a proper appreciation of the way in which causality may be investigated in clinical trials would lead to an improvement in design and analysis of short-term trials in asthma.

Original language	English
Pages (from-to)	779-791
Number of pages	13
Journal	Drug Information Journal
Volume	27
Issue number	3
DOIs	https://doi.org/10.1177/009286159302700321
Publication status	Published - Jul 1993
Externally published	Yes

Keywords

Baselines
Bioequivalence
Pharmacokinetics
Provocation
Repeated measures

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10.1177/009286159302700321

Cite this

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KW - Pharmacokinetics

KW - Provocation

KW - Repeated measures

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Statistical issues in short-term trials in asthma

Abstract

Keywords

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