@article{560466fdb77e407cbbdc511d0e36225e,
title = "Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects",
abstract = "Single-cell RNA-sequencing analysis reveals functions of lineage-specifying transcription factors underlying congenital defects in heart development.",
author = "\{de Soysa\}, \{T. Yvanka\} and Ranade, \{Sanjeev S.\} and Satoshi Okawa and Srikanth Ravichandran and Yu Huang and Salunga, \{Hazel T.\} and Amelia Schricker and \{del Sol\}, Antonio and Gifford, \{Casey A.\} and Deepak Srivastava",
note = "Funding Information: Acknowledgements We thank B. Bruneau and members of the Srivastava laboratory for helpful discussion and feedback and C. Trapnell for guidance on single-cell RNA-sequencing analysis. We acknowledge the Gladstone Histology and Light Microscopy Core, the Gladstone Genomics Core and the Gladstone Bioinformatics Core for their technical expertise and the Gladstone Animal Facility for support with mouse colony maintenance. We thank T. Marsh, J. Debnath, H. Yin, F. Chanut, B. Taylor, T. Roberts and G. Maki for their assistance with imaging, literature review, editing and graphics. We thank M. Haeussler and M. Speir for formatting and hosting the processed datasets on the UCSC cell browser. T.Y.d.S. was supported by the UCSF Chancellor{\textquoteright}s Fellowship, Genentech Foundation Fellowship, Discovery Fellows Program and Phi Beta Kappa Graduate Scholarship. C.A.G. is a HHMI fellow of the Damon Runyon Cancer Research Foundation (DRG-2206-14). S.S.R. is a Winslow Fellow. D.S. is supported by the National Heart Lung and Blood Institute (R01 HL057181, P01 HL089707, UM1HL098179, UM1HL128761), the California Institute for Regenerative Medicine (DISC2-09098), the Roddenberry Foundation, the L. K. Whittier Foundation, and the Younger Family Fund. S.O. is supported by an FNR CORE grant (C15/BM/10397420) and S.R. is supported by the University of Luxembourg IRP Grant (R-AGR-3227-11). This work was also supported by NIH/NCRR grant C06 RR018928 to the Gladstone Institutes. Publisher Copyright: {\textcopyright} 2019, {\textcopyright} 2019, The Author(s), under exclusive licence to Springer Nature Limited.",
year = "2019",
month = aug,
day = "1",
doi = "10.1038/s41586-019-1414-x",
language = "English",
volume = "572",
pages = "120--124",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Research",
number = "7767",
}