TY - JOUR
T1 - Serologic Evidence of Circulation of Six Arboviruses (Dengue Virus, Chikungunya Virus, Zika Virus, Rift Valley Virus, Yellow Fever Virus, Crimean-Congo Hemorrhagic Fever Virus) in Four Regions of Burkina Faso, West Africa
AU - Sanou, Armel Moumouni
AU - Nikiéma, Achille Sindimbasba
AU - Sausy, Aurélie
AU - Diendéré, Jeoffray
AU - Ouattara, Mathuola Nina Genéviève
AU - Badiel, Arielle Bettina Sandra
AU - Bonkoungou, Isidore
AU - Ouédraogo, Henri Gautier
AU - Hübschen, Judith M.
N1 - Funding:
This study was financially supported by the Luxembourg government through the Ministry of Foreign and European Affairs, Defence, Development Cooperation and Foreign Trade and the Luxembourg Institute of Health (“Microbiology for Development” project) as well as the Institut de Recherche en Sciences de la Santé (IRSS) in Burkina Faso.
Publisher Copyright:
© 2025 by the authors.
PY - 2025/12/9
Y1 - 2025/12/9
N2 - Apart from some information on dengue virus (DENV), there is limited data on the circulation of arboviruses in Burkina Faso. The aim of this study was to investigate antibody prevalence against six arboviruses in four regions of the country to document previous virus exposure. Serum samples collected between August 2018 and December 2022 from people infected with viral hepatitis B and C in Bobo-Dioulasso were used to detect IgG antibodies against DENV, Chikungunya virus (CHIKV), Zika virus (ZIKV), Yellow fever virus (YFV), Rift Valley fever virus (RVFV) and Crimean-Congo hemorrhagic fever virus (CCHFV) using commercial ELISA kits. A total of 1808 serum samples, accompanied by basic epidemiologic data (sex, age and residency) were included in this study. We observed an IgG antibodies seroprevalence of 75.4% for DENV, 30.8% for CHIKV, 2.9% for ZIKV, 1.2% for RVFV, 1.1% for CCHFV and 1.1% for YFV. Age, sex, and place of residence were significantly associated with seropositivity for DENV and age and sex with CHIKV seropositivity. The results suggested widespread circulation of DENV and CHIKV and possible circulation of CCHFV and RVFV in humans in Burkina Faso. The importance of strengthening arbovirus surveillance by including additional arboviruses in the diagnostic panel is emphasized.
AB - Apart from some information on dengue virus (DENV), there is limited data on the circulation of arboviruses in Burkina Faso. The aim of this study was to investigate antibody prevalence against six arboviruses in four regions of the country to document previous virus exposure. Serum samples collected between August 2018 and December 2022 from people infected with viral hepatitis B and C in Bobo-Dioulasso were used to detect IgG antibodies against DENV, Chikungunya virus (CHIKV), Zika virus (ZIKV), Yellow fever virus (YFV), Rift Valley fever virus (RVFV) and Crimean-Congo hemorrhagic fever virus (CCHFV) using commercial ELISA kits. A total of 1808 serum samples, accompanied by basic epidemiologic data (sex, age and residency) were included in this study. We observed an IgG antibodies seroprevalence of 75.4% for DENV, 30.8% for CHIKV, 2.9% for ZIKV, 1.2% for RVFV, 1.1% for CCHFV and 1.1% for YFV. Age, sex, and place of residence were significantly associated with seropositivity for DENV and age and sex with CHIKV seropositivity. The results suggested widespread circulation of DENV and CHIKV and possible circulation of CCHFV and RVFV in humans in Burkina Faso. The importance of strengthening arbovirus surveillance by including additional arboviruses in the diagnostic panel is emphasized.
KW - Burkina Faso
KW - arbovirus
KW - risk factors
KW - seroprevalence
UR - https://www.scopus.com/pages/publications/105026807005
UR - https://pubmed.ncbi.nlm.nih.gov/41441581/
U2 - 10.3390/tropicalmed10120345
DO - 10.3390/tropicalmed10120345
M3 - Article
C2 - 41441581
AN - SCOPUS:105026807005
SN - 2414-6366
VL - 10
JO - Tropical Medicine and Infectious Disease
JF - Tropical Medicine and Infectious Disease
IS - 12
M1 - 345
ER -