@article{56f9bf5029cb4b299ae95addc20ce0c3,
title = "RNAs in brain and heart diseases",
abstract = "In the era of single-cell analysis, one always has to keep in mind the systemic nature of various diseases and how these diseases could be optimally studied. Comorbidities of the heart in neurological diseases as well as of the brain in cardiovascular diseases are prevalent, but how interactions in the brain–heart axis affect disease development and progression has been poorly addressed. Several brain and heart diseases share common risk factors. A better understanding of the brain–heart interactions will provide better insights for future treatment and personalization of healthcare, for heart failure patients{\textquoteright} benefit notably. We review here emerging evidence that studying noncoding RNAs in the brain–heart axis could be pivotal in understanding these interactions. We also introduce the Special Issue of the International Journal of Molecular Sciences RNAs in Brain and Heart Diseases—EU-CardioRNA COST Action.",
keywords = "Brain, Comorbidities, Heart, Neurocardiology, Noncoding RNAs",
author = "Dimitris Beis and Inga Zerr and Fabio Martelli and Wolfram Doehner and Yvan Devaux",
note = "Funding Information: Author Contributions: D.B., Y.D., writing—original draft preparation, D.B., I.Z., F.M., W.D., Y.D.; writing— Freuvniedwin agn:dT ehdiistinwgo, rakll aisutshuoprps ohratveedrbeayd CaOndS Tag(rEeeudro tpoetahnepCuobolpisehreadtiovnersiinonS coife tnhceemaanndusTcerciphtn. ology) Action EU-CardioRNA CA17129. Yvan Devaux is supported by the National Research Fund of Luxembourg (grants # C14/BM/8225223 and C17/BM/11613033), the Ministry of Higher Education and Research of Luxembourg, and tChaerdHieoaRrNt FAo uCnAd1a7t1io2n9.- YDvaannieDl Wevaagunxe ri.s FsaubpipooMrtaerdt ebllyi itshseuNppaotirotnedal bRyetsheearIcthal iFaunnMd inofisLtruyxoefmHbeoaulrthg ((“gRraicnetrsc a# C14/BM/8225223 and C17/BM/11613033), the Ministry of Higher Education and Research of Luxembourg, and the Heart Foundation - Daniel Wagner. Fabio Martelli is supported by the Italian Ministry of Health (“Ricerca sCuoprpreonrttee”d abnydC “O5xS1T0(0E0u”r)o apneda nbyC Toeolpeethraotnio FnoiunnSdcaietinocne (aGnGdPT1e9c0h3n5oAlo).g y). Funding Information: supported by COST (European Cooperation in Science and Technology). publish the results. Conflicts of Interest: The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. Publisher Copyright: {\textcopyright} 2020 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2020",
month = may,
day = "2",
doi = "10.3390/ijms21103717",
language = "English",
volume = "21",
journal = "International Journal of Molecular Sciences",
issn = "1661-6596",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "10",
}