Preanalytics and Quality Control of Different Substrates for Circulating DNA Studies

Fay Betsou; Wim Ammerlaan

doi:10.1142/9789811244681_0002

Preanalytics and Quality Control of Different Substrates for Circulating DNA Studies

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

In this chapter, we review the most critical preanalytical factors in cirDNA analysis by sequencing, dPCR or BEAMing digital PCR, and methylation-specific PCR, with a focus on applications other than prenatal testing. We also review mitigation of preanalytical risks by the use of quality control procedures.

Original language	English
Title of host publication	Cell-Free Circulating DNA
Subtitle of host publication	Purification and Analysis Techniques
Editors	Kristina Warton, Goli Samimi
Publisher	World Scientific Publishing Co.
Chapter	2
Pages	21-46
Number of pages	26
ISBN (Electronic)	9789811244681
ISBN (Print)	9789811244674
DOIs	https://doi.org/10.1142/9789811244681_0002 https://doi.org/10.1142/9789811244681_0002
Publication status	Published - Aug 2022
Externally published	Yes

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title = "Preanalytics and Quality Control of Different Substrates for Circulating DNA Studies",

abstract = "In this chapter, we review the most critical preanalytical factors in cirDNA analysis by sequencing, dPCR or BEAMing digital PCR, and methylation-specific PCR, with a focus on applications other than prenatal testing. We also review mitigation of preanalytical risks by the use of quality control procedures.",

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AB - In this chapter, we review the most critical preanalytical factors in cirDNA analysis by sequencing, dPCR or BEAMing digital PCR, and methylation-specific PCR, with a focus on applications other than prenatal testing. We also review mitigation of preanalytical risks by the use of quality control procedures.

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DO - 10.1142/9789811244681_0002

M3 - Chapter

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BT - Cell-Free Circulating DNA

A2 - Warton, Kristina

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PB - World Scientific Publishing Co.

ER -

Preanalytics and Quality Control of Different Substrates for Circulating DNA Studies

Abstract

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