In this chapter, we review the most critical preanalytical factors in cirDNA analysis by sequencing, dPCR or BEAMing digital PCR, and methylation-specific PCR, with a focus on applications other than prenatal testing. We also review mitigation of preanalytical risks by the use of quality control procedures.
|Title of host publication||Cell-Free Circulating DNA|
|Subtitle of host publication||Purification and Analysis Techniques|
|Editors||Kristina Warton, Goli Samimi|
|Publisher||World Scientific Publishing Co.|
|Number of pages||26|
|Publication status||Published - Aug 2022|