Preanalytics and Quality Control of Different Substrates for Circulating DNA Studies

Fay Betsou, Wim Ammerlaan

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

In this chapter, we review the most critical preanalytical factors in cirDNA analysis by sequencing, dPCR or BEAMing digital PCR, and methylation-specific PCR, with a focus on applications other than prenatal testing. We also review mitigation of preanalytical risks by the use of quality control procedures.
Original languageEnglish
Title of host publicationCell-Free Circulating DNA: Purification and Analysis Techniques
EditorsKristina Warton, Goli Samimi
PublisherWorld Scientific
Chapter2
Pages21-46
Number of pages26
ISBN (Electronic)978-981-124-469-8
ISBN (Print)978-981-124-467-4
DOIs
Publication statusPublished - Aug 2022

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