Preanalytical challenges-time for solutions

Giuseppe Lippi*, Fay Betsou, Janne Cadamuro, Michael Cornes, Michael Fleischhacker, Palle Fruekilde, Michael Neumaier, Mads Nybo, Andrea Padoan, Mario Plebani, Laura Sciacovelli, Pieter Vermeersch, Alexander Von Meyer, Ana Maria Simundic

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)


The European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE) was originally established in 2013, with the main aims of (i) promoting the importance of quality in the preanalytical phase of the testing process, (ii) establishing best practices and providing guidance for critical activities in the preanalytical phase, (iii) developing and disseminating European surveys for exploring practices concerning preanalytical issues, (iv) organizing meetings, workshops, webinars or specific training courses on preanalytical issues. As education is a core activity of the WG-PRE, a series of European conferences have been organized every second year across Europe. This collective article summarizes the leading concepts expressed during the lectures of the fifth EFLM Preanalytical Conference "Preanalytical Challenges-Time for solutions", held in Zagreb, 22-23 March, 2019. The topics covered include sample stability, preanalytical challenges in hematology testing, feces analysis, bio-banking, liquid profiling, mass spectrometry, next generation sequencing, laboratory automation, the importance of knowing and measuring the exact sampling time, technology aids in managing inappropriate utilization of laboratory resources, management of hemolyzed samples and preanalytical quality indicators.

Original languageEnglish
Pages (from-to)974-981
Number of pages8
JournalClinical Chemistry and Laboratory Medicine
Issue number7
Publication statusPublished - 1 Jul 2019


  • education
  • errors
  • laboratory medicine
  • preanalytical phase
  • quality


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