Prédispositions génétiques au cancer du sein

G. Berchem

Prédispositions génétiques au cancer du sein

Translated title of the contribution: Genetic predisposition for breast cancer

G. Berchem^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Approximately 10 to 15% of patients with breast cancer have a family history of breast and ovarian cancer. In about half of these patients a mutation in the genes of BRCA1 or 2 can be detected. A mutation in one of these genes entails a significant increase in the lifetime breast cancer risk, which can be up to 75%. These mutations have profound medical as well as psychological implications. In this paper I will discuss some of these implications and suggest a management scheme for these patients.

Translated title of the contribution	Genetic predisposition for breast cancer
Original language	French
Pages (from-to)	65-67
Number of pages	3
Journal	Sein
Volume	13
Issue number	2
Publication status	Published - May 2003
Externally published	Yes

Keywords

BRCA
Familial breast cancer
Prevention
Screening

Cite this

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abstract = "Approximately 10 to 15% of patients with breast cancer have a family history of breast and ovarian cancer. In about half of these patients a mutation in the genes of BRCA1 or 2 can be detected. A mutation in one of these genes entails a significant increase in the lifetime breast cancer risk, which can be up to 75%. These mutations have profound medical as well as psychological implications. In this paper I will discuss some of these implications and suggest a management scheme for these patients.",

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N2 - Approximately 10 to 15% of patients with breast cancer have a family history of breast and ovarian cancer. In about half of these patients a mutation in the genes of BRCA1 or 2 can be detected. A mutation in one of these genes entails a significant increase in the lifetime breast cancer risk, which can be up to 75%. These mutations have profound medical as well as psychological implications. In this paper I will discuss some of these implications and suggest a management scheme for these patients.

AB - Approximately 10 to 15% of patients with breast cancer have a family history of breast and ovarian cancer. In about half of these patients a mutation in the genes of BRCA1 or 2 can be detected. A mutation in one of these genes entails a significant increase in the lifetime breast cancer risk, which can be up to 75%. These mutations have profound medical as well as psychological implications. In this paper I will discuss some of these implications and suggest a management scheme for these patients.

KW - BRCA

KW - Familial breast cancer

KW - Prevention

KW - Screening

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M3 - Article

AN - SCOPUS:0038487070

SN - 1163-1961

VL - 13

SP - 65

EP - 67

JO - Sein

JF - Sein

IS - 2

ER -

Prédispositions génétiques au cancer du sein

Abstract

Keywords

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