Abstract
Approximately 10 to 15% of patients with breast cancer have a family history of breast and ovarian cancer. In about half of these patients a mutation in the genes of BRCA1 or 2 can be detected. A mutation in one of these genes entails a significant increase in the lifetime breast cancer risk, which can be up to 75%. These mutations have profound medical as well as psychological implications. In this paper I will discuss some of these implications and suggest a management scheme for these patients.
| Translated title of the contribution | Genetic predisposition for breast cancer |
|---|---|
| Original language | French |
| Pages (from-to) | 65-67 |
| Number of pages | 3 |
| Journal | Sein |
| Volume | 13 |
| Issue number | 2 |
| Publication status | Published - May 2003 |
| Externally published | Yes |
Keywords
- BRCA
- Familial breast cancer
- Prevention
- Screening