Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system: Results of the RODEO study team

Maíra Degiovani Stein; José Humberto T.G. Fregnani; Cristovam Scapulatempo; Allini Mafra; Natália Campacci; Adhemar Longatto-Filho; Teóclito Saccheto De Carvalho; Fábio De Paula Mateus; Eduardo Tadeu Da Silva; Michele M.Castro Alves; Fábio Cardoso De Lima; Erlaine Martins Suriano; Eduardo C.A. Da Silva; Sandra M. Da Silva; Ligia Maria Kerr; Lucas F.A. Machado; Edmundo C. Mauad

doi:10.1309/AJCPWL36JXMRESFH

Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system: Results of the RODEO study team

Maíra Degiovani Stein
, José Humberto T.G. Fregnani
, Cristovam Scapulatempo
, Allini Mafra
, Natália Campacci
, Adhemar Longatto-Filho^*
, Teóclito Saccheto De Carvalho
, Fábio De Paula Mateus
, Eduardo Tadeu Da Silva
, Michele M.Castro Alves
, Fábio Cardoso De Lima
, Erlaine Martins Suriano
, Eduardo C.A. Da Silva
, Sandra M. Da Silva
, Ligia Maria Kerr
, Lucas F.A. Machado
, Edmundo C. Mauad

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

13 Citations (Scopus)

Abstract

Objectives: To assess whether automated screening in the cytologic examination of Papanicolaou smear slides results in smaller margins of error than manual screening. Methods: We compared cytotechnologists' performance and reproducibility of manual and automated screening of 10,165 consecutive cervical cytology slides examined at Barretos Cancer Hospital using the FocalPoint system. Results: In total, 83% of atypical squamous cells of undetermined significance and greater were classified as quintiles 1 and 2; no high-grade squamous intraepithelial lesions and greater were observed in quintile 5. No statistically significant differences were found between manual and automated screening, using cervical biopsy specimens as the gold standard. Conclusions: FocalPoint safely screened high-grade lesions, which can be valuable for high-workload routines.

Original language	English
Pages (from-to)	567-571
Number of pages	5
Journal	American Journal of Clinical Pathology
Volume	140
Issue number	4
DOIs	https://doi.org/10.1309/AJCPWL36JXMRESFH
Publication status	Published - Oct 2013
Externally published	Yes

Keywords

Automation
FocalPoint
Pap test
Quality control
SurePath

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10.1309/AJCPWL36JXMRESFH

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Stein, M. D., Fregnani, J. H. T. G., Scapulatempo, C., Mafra, A., Campacci, N., Longatto-Filho, A., De Carvalho, T. S., De Paula Mateus, F., Da Silva, E. T., Alves, M. M. C., De Lima, F. C., Suriano, E. M., Da Silva, E. C. A., Da Silva, S. M., Kerr, L. M., Machado, L. F. A., & Mauad, E. C. (2013). Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system: Results of the RODEO study team. American Journal of Clinical Pathology, 140(4), 567-571. https://doi.org/10.1309/AJCPWL36JXMRESFH

@article{bdd3610225fe4eeba01c895b93e9a0e6,

title = "Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system: Results of the RODEO study team",

abstract = "Objectives: To assess whether automated screening in the cytologic examination of Papanicolaou smear slides results in smaller margins of error than manual screening. Methods: We compared cytotechnologists' performance and reproducibility of manual and automated screening of 10,165 consecutive cervical cytology slides examined at Barretos Cancer Hospital using the FocalPoint system. Results: In total, 83\% of atypical squamous cells of undetermined significance and greater were classified as quintiles 1 and 2; no high-grade squamous intraepithelial lesions and greater were observed in quintile 5. No statistically significant differences were found between manual and automated screening, using cervical biopsy specimens as the gold standard. Conclusions: FocalPoint safely screened high-grade lesions, which can be valuable for high-workload routines.",

keywords = "Automation, FocalPoint, Pap test, Quality control, SurePath",

author = "Stein, \{Ma{\'i}ra Degiovani\} and Fregnani, \{Jos{\'e} Humberto T.G.\} and Cristovam Scapulatempo and Allini Mafra and Nat{\'a}lia Campacci and Adhemar Longatto-Filho and \{De Carvalho\}, \{Te{\'o}clito Saccheto\} and \{De Paula Mateus\}, F{\'a}bio and \{Da Silva\}, \{Eduardo Tadeu\} and Alves, \{Michele M.Castro\} and \{De Lima\}, \{F{\'a}bio Cardoso\} and Suriano, \{Erlaine Martins\} and \{Da Silva\}, \{Eduardo C.A.\} and \{Da Silva\}, \{Sandra M.\} and Kerr, \{Ligia Maria\} and Machado, \{Lucas F.A.\} and Mauad, \{Edmundo C.\}",

year = "2013",

month = oct,

doi = "10.1309/AJCPWL36JXMRESFH",

language = "English",

volume = "140",

pages = "567--571",

journal = "American Journal of Clinical Pathology",

issn = "0002-9173",

publisher = "Oxford University Press",

number = "4",

}

Stein, MD, Fregnani, JHTG, Scapulatempo, C, Mafra, A, Campacci, N, Longatto-Filho, A, De Carvalho, TS, De Paula Mateus, F, Da Silva, ET, Alves, MMC, De Lima, FC, Suriano, EM, Da Silva, ECA, Da Silva, SM, Kerr, LM, Machado, LFA & Mauad, EC 2013, 'Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system: Results of the RODEO study team', American Journal of Clinical Pathology, vol. 140, no. 4, pp. 567-571. https://doi.org/10.1309/AJCPWL36JXMRESFH

Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system: Results of the RODEO study team. / Stein, Maíra Degiovani; Fregnani, José Humberto T.G.; Scapulatempo, Cristovam et al.
In: American Journal of Clinical Pathology, Vol. 140, No. 4, 10.2013, p. 567-571.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system

T2 - Results of the RODEO study team

AU - Stein, Maíra Degiovani

AU - Fregnani, José Humberto T.G.

AU - Scapulatempo, Cristovam

AU - Mafra, Allini

AU - Campacci, Natália

AU - Longatto-Filho, Adhemar

AU - De Carvalho, Teóclito Saccheto

AU - De Paula Mateus, Fábio

AU - Da Silva, Eduardo Tadeu

AU - Alves, Michele M.Castro

AU - De Lima, Fábio Cardoso

AU - Suriano, Erlaine Martins

AU - Da Silva, Eduardo C.A.

AU - Da Silva, Sandra M.

AU - Kerr, Ligia Maria

AU - Machado, Lucas F.A.

AU - Mauad, Edmundo C.

PY - 2013/10

Y1 - 2013/10

N2 - Objectives: To assess whether automated screening in the cytologic examination of Papanicolaou smear slides results in smaller margins of error than manual screening. Methods: We compared cytotechnologists' performance and reproducibility of manual and automated screening of 10,165 consecutive cervical cytology slides examined at Barretos Cancer Hospital using the FocalPoint system. Results: In total, 83% of atypical squamous cells of undetermined significance and greater were classified as quintiles 1 and 2; no high-grade squamous intraepithelial lesions and greater were observed in quintile 5. No statistically significant differences were found between manual and automated screening, using cervical biopsy specimens as the gold standard. Conclusions: FocalPoint safely screened high-grade lesions, which can be valuable for high-workload routines.

AB - Objectives: To assess whether automated screening in the cytologic examination of Papanicolaou smear slides results in smaller margins of error than manual screening. Methods: We compared cytotechnologists' performance and reproducibility of manual and automated screening of 10,165 consecutive cervical cytology slides examined at Barretos Cancer Hospital using the FocalPoint system. Results: In total, 83% of atypical squamous cells of undetermined significance and greater were classified as quintiles 1 and 2; no high-grade squamous intraepithelial lesions and greater were observed in quintile 5. No statistically significant differences were found between manual and automated screening, using cervical biopsy specimens as the gold standard. Conclusions: FocalPoint safely screened high-grade lesions, which can be valuable for high-workload routines.

KW - Automation

KW - FocalPoint

KW - Pap test

KW - Quality control

KW - SurePath

UR - https://www.scopus.com/pages/publications/84884911970

U2 - 10.1309/AJCPWL36JXMRESFH

DO - 10.1309/AJCPWL36JXMRESFH

M3 - Article

C2 - 24045555

AN - SCOPUS:84884911970

SN - 0002-9173

VL - 140

SP - 567

EP - 571

JO - American Journal of Clinical Pathology

JF - American Journal of Clinical Pathology

IS - 4

ER -

Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system: Results of the RODEO study team

Abstract

Keywords

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