TY - JOUR
T1 - Performance and reproducibility of gynecologic cytology interpretation using the focalpoint system
T2 - Results of the RODEO study team
AU - Stein, Maíra Degiovani
AU - Fregnani, José Humberto T.G.
AU - Scapulatempo, Cristovam
AU - Mafra, Allini
AU - Campacci, Natália
AU - Longatto-Filho, Adhemar
AU - De Carvalho, Teóclito Saccheto
AU - De Paula Mateus, Fábio
AU - Da Silva, Eduardo Tadeu
AU - Alves, Michele M.Castro
AU - De Lima, Fábio Cardoso
AU - Suriano, Erlaine Martins
AU - Da Silva, Eduardo C.A.
AU - Da Silva, Sandra M.
AU - Kerr, Ligia Maria
AU - Machado, Lucas F.A.
AU - Mauad, Edmundo C.
PY - 2013/10
Y1 - 2013/10
N2 - Objectives: To assess whether automated screening in the cytologic examination of Papanicolaou smear slides results in smaller margins of error than manual screening. Methods: We compared cytotechnologists' performance and reproducibility of manual and automated screening of 10,165 consecutive cervical cytology slides examined at Barretos Cancer Hospital using the FocalPoint system. Results: In total, 83% of atypical squamous cells of undetermined significance and greater were classified as quintiles 1 and 2; no high-grade squamous intraepithelial lesions and greater were observed in quintile 5. No statistically significant differences were found between manual and automated screening, using cervical biopsy specimens as the gold standard. Conclusions: FocalPoint safely screened high-grade lesions, which can be valuable for high-workload routines.
AB - Objectives: To assess whether automated screening in the cytologic examination of Papanicolaou smear slides results in smaller margins of error than manual screening. Methods: We compared cytotechnologists' performance and reproducibility of manual and automated screening of 10,165 consecutive cervical cytology slides examined at Barretos Cancer Hospital using the FocalPoint system. Results: In total, 83% of atypical squamous cells of undetermined significance and greater were classified as quintiles 1 and 2; no high-grade squamous intraepithelial lesions and greater were observed in quintile 5. No statistically significant differences were found between manual and automated screening, using cervical biopsy specimens as the gold standard. Conclusions: FocalPoint safely screened high-grade lesions, which can be valuable for high-workload routines.
KW - Automation
KW - FocalPoint
KW - Pap test
KW - Quality control
KW - SurePath
UR - http://www.scopus.com/inward/record.url?scp=84884911970&partnerID=8YFLogxK
U2 - 10.1309/AJCPWL36JXMRESFH
DO - 10.1309/AJCPWL36JXMRESFH
M3 - Article
C2 - 24045555
AN - SCOPUS:84884911970
SN - 0002-9173
VL - 140
SP - 567
EP - 571
JO - American Journal of Clinical Pathology
JF - American Journal of Clinical Pathology
IS - 4
ER -