Patterns of sequelae in women with a history of localized breast cancer: Results from the french vican survey

Lidia Delrieu, Liacine Bouaoun, Douae El Fatouhi, Elise Dumas, Anne Deborah Bouhnik, Hugo Noelle, Emmanuelle Jacquet, Anne Sophie Hamy, Florence Coussy, Fabien Reyal, Pierre Etienne Heudel, Marc Karim Bendiane, Baptiste Fournier, Mauricette Michallet, Béatrice Fervers, Guy Fagherazzi, Olivia Pérol*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Breast cancer (BC) remains complex for women both physically and psychologically. The objectives of this study were to (1) assess the evolution of the main sequelae and treatment two and five years after diagnosis in women with early‐stage breast cancer, (2) explore patterns of sequelae associated with given sociodemographic, clinical, and lifestyle factors. The current analysis was based on 654 localized BC patients enrolled in the French nationwide longitudinal survey “vie après cancer” VICAN (January–June 2010). Information about study participants was collected at enrollment, two and five years after diagnosis. Changes over time of the main sequelae were analyzed and latent class analysis was performed to identify patterns of sequelae related to BC five years after diagnosis. The mean age (±SD) of study participants at inclusion was 49.7 (±10.5) years old. Six main classes of sequelae were identified two years and five years post‐diagnosis (functional, pain, esthetic, fatigue, psychological, and gynecological). A significant decrease was observed for fatigue (p = 0.03) and an increase in cognitive sequelae was reported (p = 0.03). Two latent classes were identified—functional and esthetic patterns. Substantial sequelae remain up to five years after BC diagnosis. Changes in patient care pathways are needed to identify BC patients at a high risk.

Original languageEnglish
Article number1161
Pages (from-to)1-18
Number of pages18
JournalCancers
Volume13
Issue number5
DOIs
Publication statusPublished - 8 Mar 2021

Keywords

  • Breast cancer
  • Prevention
  • Sequelae
  • VICAN

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