TY - JOUR
T1 - Pace of aging, family environment and cognitive skills in children and adolescents
AU - Niccodemi, Gianmaria
AU - Menta, Giorgia
AU - Turner, Jonathan
AU - D'Ambrosio, Conchita
N1 - Acknowledgments
We thank Giovanni Fiorito and Anthony Lepinteur for very useful suggestions. We are extremely grateful to all the families who took part in this study, the midwives for their help in recruiting them, and the whole ALSPAC team, which includes interviewers, computer and labo- ratory technicians, clerical workers, research scientists, volunteers, managers, receptionists and nurses. The UK Medical Research Council and Wellcome (Grant ref: 217065/Z/19/Z) and the University of Bristol provide core support for ALSPAC. This publication is the work of the authors and all authors will serve as guarantors for the contents of this paper. A comprehensive list of grants funding the ALSPAC project is available on their website (http://www.bristol.ac.uk/alspac/external /documents/grant-acknowledgements.pdf). Financial support from the Fonds National de la Recherche Luxembourg (Grant C19/SC/13650569/ALAC) is gratefully acknowledged.
© 2022 The Authors.
PY - 2022/12
Y1 - 2022/12
N2 - Pace of aging is an epigenetic clock which captures the speed at which someone is biologically aging compared to the chronological-age peers. We here use data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate the interrelation between the study children's parental social class at birth, and their pace of aging and cognitive skills measures in childhood and adolescence. We show that children from lower parental social classes display faster pace of aging and that the social class gradient in pace of aging is strongest in adolescence. About one third of this association can be explained by other socio-economic and demographic covariates, as well as life events. Similarly, study children's pace of aging manifests a negative association with their measures of cognitive skills in late adolescence only. This association becomes stronger as the contemporary pace of aging of the mother becomes faster. Our results seem to identify adolescence as the period of life when pace of aging, family environment and cognitive skills measures begin to interact.
AB - Pace of aging is an epigenetic clock which captures the speed at which someone is biologically aging compared to the chronological-age peers. We here use data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate the interrelation between the study children's parental social class at birth, and their pace of aging and cognitive skills measures in childhood and adolescence. We show that children from lower parental social classes display faster pace of aging and that the social class gradient in pace of aging is strongest in adolescence. About one third of this association can be explained by other socio-economic and demographic covariates, as well as life events. Similarly, study children's pace of aging manifests a negative association with their measures of cognitive skills in late adolescence only. This association becomes stronger as the contemporary pace of aging of the mother becomes faster. Our results seem to identify adolescence as the period of life when pace of aging, family environment and cognitive skills measures begin to interact.
UR - https://pubmed.ncbi.nlm.nih.gov/36387015
U2 - 10.1016/j.ssmph.2022.101280
DO - 10.1016/j.ssmph.2022.101280
M3 - Article
C2 - 36387015
SN - 2352-8273
VL - 20
JO - SSM - Population Health
JF - SSM - Population Health
M1 - 101280
ER -