Oncomodulation by human cytomegalovirus: Novel clinical findings open new roads

Martin Michaelis, Peter Baumgarten, Michel Mittelbronn, Pablo Hernáiz Driever, Hans Wilhelm Doerr, Jindrich Cinatl*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

47 Citations (Scopus)

Abstract

The question whether human cytomegalovirus may affect cancer diseases has been discussed (very controversially) for decades. There are convinced believers and strict opponents of the idea that HCMV might be able to play a role in the course of cancer diseases. In parallel, the number of published reports on the topic is growing. Recently published and presented (Ranganathan P, Clark P, Kuo JS, Salamat S, Kalejta RF. A Survey of Human Cytomegalovirus Genomic Loci Present in Glioblastoma Multiforme Tissue Samples. 35th Annual International Herpes Workshop, Salt Lake City, 2010) data on HCMV detection in glioblastoma tissues and colocalisation of HCMV proteins with cellular proteins known to be relevant for glioblastoma progression motivated us to recapitulate the current state of evidence.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalMedical Microbiology and Immunology
Volume200
Issue number1
DOIs
Publication statusPublished - Feb 2011
Externally publishedYes

Keywords

  • Cancer
  • Cytomegalovirus
  • Glioblastoma
  • Neuroblastoma
  • Oncomodulation
  • Tumour virus

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