Nutritional risk factors of type 2 diabetes – Contribution of the French NutriNet-Santé cohort to scientific knowledge

Pauline Duquenne*, Léopold K. Fezeu, Laurent Bourhis, Paola Yvroud, Bernard Srour, Emmanuelle Kesse-Guyot, Chantal Julia, Julia Baudry, Emmanuel Cosson, Sopio Tatulashvili, Pilar Galan, Serge Hercberg, Mathilde Touvier, Valentina A. Andreeva

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Given the increasing prevalence of type 2 diabetes (T2D) worldwide, it is important to better understand its risk and protective factors in order to guide future prevention and disease management policies. Observational studies on a large scale provide valuable information in this regard. The NutriNet-Santé study is a French prospective online cohort, launched in 2009. Since then, 12 original articles focused on T2D have been published. Of those studies, 11 used a prospective design (mean follow-up: 4 to 9 years), analyzing risk or protective factors for T2D related to dietary intake, with samples ranging from 33,256 to 107,377 participants. Consumption of ultra-processed foods, exposure to certain pesticide mixtures or the late timing of the first food intake were associated with a higher risk of T2D. On the other hand, greater adherence to French dietary guidelines and higher consumption of organic food were associated with a lower risk of T2D. Other studies in relation to T2D are currently underway in the NutriNet-Santé cohort, focusing on adherence to sustainable diets, exposure to certain additives and contaminants linked to food processing, and mental health disorders.

Original languageEnglish
Pages (from-to)164-175
Number of pages12
JournalCahiers de Nutrition et de Dietetique
Volume60
Issue number3
DOIs
Publication statusPublished - Jun 2025
Externally publishedYes

Keywords

  • Epidemiological study
  • Nutrition
  • Public health
  • Review
  • Type 2 diabetes

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