NK cells in oncology

Sigrid De Wilde, Guy Berchem*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)


NK cells have a dual role in human cancer. First they are responsible for various haematological malignancies like the aggressive NK cell leukemia, the extra nodal NK/T cell lymphoma of the nasal type or the blastic NK cell lymphoma. Secondly NK cells have shown great promise in the therapeutic area since the 1970s. Indeed NK cell therapeutic strategies are being tested in vitro and in vivo in human cancer. As the understanding of NK cell immunology increases we will probably be able to use these cells in adoptive immunotherapy strategies to tackle human cancer in the future.

Original languageEnglish
Title of host publicationNatural Killer Cells
Subtitle of host publicationAt the Forefront of Modern Immunology
PublisherSpringer Berlin Heidelberg
Number of pages8
ISBN (Print)9783642023088
Publication statusPublished - 2010
Externally publishedYes


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