NK cells have a dual role in human cancer. First they are responsible for various haematological malignancies like the aggressive NK cell leukemia, the extra nodal NK/T cell lymphoma of the nasal type or the blastic NK cell lymphoma. Secondly NK cells have shown great promise in the therapeutic area since the 1970s. Indeed NK cell therapeutic strategies are being tested in vitro and in vivo in human cancer. As the understanding of NK cell immunology increases we will probably be able to use these cells in adoptive immunotherapy strategies to tackle human cancer in the future.
|Title of host publication||Natural Killer Cells|
|Subtitle of host publication||At the Forefront of Modern Immunology|
|Publisher||Springer Berlin Heidelberg|
|Number of pages||8|
|Publication status||Published - 2010|