Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge niphates sp

Nathalie Legrave; Souhir Hamrouni-Buonomo; Maeva Dufies; Vincent Guérineau; Jean Vacelet; Patrick Auberger; Philippe Amade; Mohamed Mehiri

doi:10.3390/md11072282

Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge niphates sp

Nathalie Legrave, Souhir Hamrouni-Buonomo, Maeva Dufies, Vincent Guérineau, Jean Vacelet, Patrick Auberger, Philippe Amade, Mohamed Mehiri^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Abstract

A new C₄₇ polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.

Original language	English
Pages (from-to)	2282-2292
Number of pages	11
Journal	Marine Drugs
Volume	11
Issue number	7
DOIs	https://doi.org/10.3390/md11072282
Publication status	Published - Jul 2013
Externally published	Yes

Keywords

Haplosclerida
Highly oxygenated polyacetylenes
Marine natural products
Marine sponges
Porifera

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10.3390/md11072282

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title = "Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge niphates sp",

abstract = "A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.",

keywords = "Haplosclerida, Highly oxygenated polyacetylenes, Marine natural products, Marine sponges, Porifera",

author = "Nathalie Legrave and Souhir Hamrouni-Buonomo and Maeva Dufies and Vincent Gu{\'e}rineau and Jean Vacelet and Patrick Auberger and Philippe Amade and Mohamed Mehiri",

year = "2013",

month = jul,

doi = "10.3390/md11072282",

language = "English",

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pages = "2282--2292",

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T1 - Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge niphates sp

AU - Legrave, Nathalie

AU - Hamrouni-Buonomo, Souhir

AU - Dufies, Maeva

AU - Guérineau, Vincent

AU - Vacelet, Jean

AU - Auberger, Patrick

AU - Amade, Philippe

AU - Mehiri, Mohamed

PY - 2013/7

Y1 - 2013/7

N2 - A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.

AB - A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.

KW - Haplosclerida

KW - Highly oxygenated polyacetylenes

KW - Marine natural products

KW - Marine sponges

KW - Porifera

UR - http://www.scopus.com/inward/record.url?scp=84880870277&partnerID=8YFLogxK

U2 - 10.3390/md11072282

DO - 10.3390/md11072282

M3 - Article

C2 - 23807547

AN - SCOPUS:84880870277

SN - 1660-3397

VL - 11

SP - 2282

EP - 2292

JO - Marine Drugs

JF - Marine Drugs

IS - 7

ER -

Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge niphates sp

Abstract

Keywords

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