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Natural chalcones as dual inhibitors of HDACs and NF-κB
B. Orlikova
,
M. Schnekenburger
, M. Zloh
, F. Golais
, M. Diederich
*
, D. Tasdemir
*
Corresponding author for this work
Research output
:
Contribution to journal
›
Article
›
Research
›
peer-review
86
Citations (Scopus)
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Keyphrases
NF-B
100%
Histone Deacetylase Inhibitor (HDACi)
100%
Natural Chalcones
100%
Dual Inhibitor
100%
Histone Deacetylase Enzymes
100%
Chalcone
62%
Inflammation
25%
IC50 Value
25%
Inhibitory Potential
25%
Enzyme Inhibitory Activity
25%
Putative Drug Targets
12%
Transcription Factor
12%
Enzyme Activity
12%
Antitumor Effect
12%
Anti-inflammatory Effect
12%
Structure-activity Relationship
12%
Glycosides
12%
Fluorescence Assay
12%
Natural Products
12%
Dual Activity
12%
Molecular Docking Studies
12%
Isoliquiritigenin
12%
Marein
12%
Butein
12%
Molecular Modeling Studies
12%
Biological Targets
12%
Pharmacology, Toxicology and Pharmaceutical Science
Histone Deacetylase
100%
Enzymes
100%
Chalcone Derivative
100%
Malignant Neoplasm
25%
Tumor Necrosis Factor
25%
Inflammation
25%
IC50
25%
Anti-Inflammatory Drug
12%
Structure Activity Relationship
12%
Fluorescence Assay
12%
Natural Product
12%
Lead Compound
12%
Transcription Factors
12%
Glycoside
12%
Isoliquiritigenin
12%
Biological Target
12%
Butein
12%
Biochemistry, Genetics and Molecular Biology
Enzyme
100%
Histone Deacetylase
100%
IC50
25%
Tumor Necrosis Factor
25%
Fluorescence Assay
12%
Structure Activity Relation
12%
Enzyme Activity
12%
Transcription Factors
12%
Molecular Model
12%
Anti-Inflammatory
12%
Biological Target
12%
Glycoside
12%