Myocardial MIBG scintigraphy: A useful clinical tool

Ines Fröhlich; Nico J. Diederich; Wilfried Pilloy; Michel Vaillant

doi:10.1007/s10072-010-0218-4

Myocardial MIBG scintigraphy: A useful clinical tool

Ines Fröhlich^*
, Nico J. Diederich
, Wilfried Pilloy
, Michel Vaillant

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

17 Citations (Scopus)

Abstract

Meta-iodbenzylguanidine scintigraphy (MIBG scintigraphy) shows reduced uptake in idiopathic Parkinson's disease (IPD), idiopathic REMsleep behavior disorder (IRBD) and Lewy body dementia (LBD), but not in other parkinsonian or dementia syndromes. We retrospectively reevaluated 50 patients. Concordance rate between last clinical diagnosis and scintigraphy diagnosis was only given in two-thirds of the patients. Confounding factors were: decreasing heart/mediastinum ratio (HMR) with progressive age, higher HMR in women and possibly interference with antihypertensive medication. Standardization of the methods and precise clinical guidelines are warranted for better clinical use.

Original language	English
Pages (from-to)	403-406
Number of pages	4
Journal	Neurological Sciences
Volume	31
Issue number	3
DOIs	https://doi.org/10.1007/s10072-010-0218-4
Publication status	Published - Jun 2010

Keywords

Idiopathic Parkinson disease
Myocardial scintigraphy

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10.1007/s10072-010-0218-4

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title = "Myocardial MIBG scintigraphy: A useful clinical tool",

abstract = "Meta-iodbenzylguanidine scintigraphy (MIBG scintigraphy) shows reduced uptake in idiopathic Parkinson's disease (IPD), idiopathic REMsleep behavior disorder (IRBD) and Lewy body dementia (LBD), but not in other parkinsonian or dementia syndromes. We retrospectively reevaluated 50 patients. Concordance rate between last clinical diagnosis and scintigraphy diagnosis was only given in two-thirds of the patients. Confounding factors were: decreasing heart/mediastinum ratio (HMR) with progressive age, higher HMR in women and possibly interference with antihypertensive medication. Standardization of the methods and precise clinical guidelines are warranted for better clinical use.",

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T2 - A useful clinical tool

AU - Fröhlich, Ines

AU - Diederich, Nico J.

AU - Pilloy, Wilfried

AU - Vaillant, Michel

PY - 2010/6

Y1 - 2010/6

N2 - Meta-iodbenzylguanidine scintigraphy (MIBG scintigraphy) shows reduced uptake in idiopathic Parkinson's disease (IPD), idiopathic REMsleep behavior disorder (IRBD) and Lewy body dementia (LBD), but not in other parkinsonian or dementia syndromes. We retrospectively reevaluated 50 patients. Concordance rate between last clinical diagnosis and scintigraphy diagnosis was only given in two-thirds of the patients. Confounding factors were: decreasing heart/mediastinum ratio (HMR) with progressive age, higher HMR in women and possibly interference with antihypertensive medication. Standardization of the methods and precise clinical guidelines are warranted for better clinical use.

AB - Meta-iodbenzylguanidine scintigraphy (MIBG scintigraphy) shows reduced uptake in idiopathic Parkinson's disease (IPD), idiopathic REMsleep behavior disorder (IRBD) and Lewy body dementia (LBD), but not in other parkinsonian or dementia syndromes. We retrospectively reevaluated 50 patients. Concordance rate between last clinical diagnosis and scintigraphy diagnosis was only given in two-thirds of the patients. Confounding factors were: decreasing heart/mediastinum ratio (HMR) with progressive age, higher HMR in women and possibly interference with antihypertensive medication. Standardization of the methods and precise clinical guidelines are warranted for better clinical use.

KW - Idiopathic Parkinson disease

KW - Myocardial scintigraphy

UR - https://www.scopus.com/pages/publications/77955879903

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DO - 10.1007/s10072-010-0218-4

M3 - Article

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AN - SCOPUS:77955879903

SN - 1590-1874

VL - 31

SP - 403

EP - 406

JO - Neurological Sciences

JF - Neurological Sciences

IS - 3

ER -

Myocardial MIBG scintigraphy: A useful clinical tool

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Keywords

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