TY - JOUR
T1 - Myocardial MIBG scintigraphy
T2 - A useful clinical tool
AU - Fröhlich, Ines
AU - Diederich, Nico J.
AU - Pilloy, Wilfried
AU - Vaillant, Michel
PY - 2010/6
Y1 - 2010/6
N2 - Meta-iodbenzylguanidine scintigraphy (MIBG scintigraphy) shows reduced uptake in idiopathic Parkinson's disease (IPD), idiopathic REMsleep behavior disorder (IRBD) and Lewy body dementia (LBD), but not in other parkinsonian or dementia syndromes. We retrospectively reevaluated 50 patients. Concordance rate between last clinical diagnosis and scintigraphy diagnosis was only given in two-thirds of the patients. Confounding factors were: decreasing heart/mediastinum ratio (HMR) with progressive age, higher HMR in women and possibly interference with antihypertensive medication. Standardization of the methods and precise clinical guidelines are warranted for better clinical use.
AB - Meta-iodbenzylguanidine scintigraphy (MIBG scintigraphy) shows reduced uptake in idiopathic Parkinson's disease (IPD), idiopathic REMsleep behavior disorder (IRBD) and Lewy body dementia (LBD), but not in other parkinsonian or dementia syndromes. We retrospectively reevaluated 50 patients. Concordance rate between last clinical diagnosis and scintigraphy diagnosis was only given in two-thirds of the patients. Confounding factors were: decreasing heart/mediastinum ratio (HMR) with progressive age, higher HMR in women and possibly interference with antihypertensive medication. Standardization of the methods and precise clinical guidelines are warranted for better clinical use.
KW - Idiopathic Parkinson disease
KW - Myocardial scintigraphy
UR - http://www.scopus.com/inward/record.url?scp=77955879903&partnerID=8YFLogxK
U2 - 10.1007/s10072-010-0218-4
DO - 10.1007/s10072-010-0218-4
M3 - Article
C2 - 20155379
AN - SCOPUS:77955879903
SN - 1590-1874
VL - 31
SP - 403
EP - 406
JO - Neurological Sciences
JF - Neurological Sciences
IS - 3
ER -