Multifunctional Heteromultimeric Constructs

Xavier Dervillez; Carole Seguin-Devaux; Jacques H. M. Cohen

Multifunctional Heteromultimeric Constructs

Xavier Dervillez (Inventor), Carole Seguin-Devaux (Inventor), Jacques H. M. Cohen (Inventor)

Research output: Patent

Abstract

The present invention is situated in the field of multimers used for targeted therapies. More particularly, the invention relates to methods for preparing multifunctional heteromultimeric protein complexes with a defined ratio of functional components and to multifunctional heteromultimeric protein complexes for directing complement-dependent cytolysis, optionally comprising a scaffold, which display three or more different functional components present in a defined relative ratio, of which one is a tracking component.

Original language	English
IPC	US 2023/0130737 A1
Publication status	Published - 27 Apr 2023

Keywords

Protein

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title = "Multifunctional Heteromultimeric Constructs",

abstract = "The present invention is situated in the field of multimers used for targeted therapies. More particularly, the invention relates to methods for preparing multifunctional heteromultimeric protein complexes with a defined ratio of functional components and to multifunctional heteromultimeric protein complexes for directing complement-dependent cytolysis, optionally comprising a scaffold, which display three or more different functional components present in a defined relative ratio, of which one is a tracking component.",

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author = "Xavier Dervillez and Carole Seguin-Devaux and Cohen, {Jacques H. M.}",

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language = "English",

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T1 - Multifunctional Heteromultimeric Constructs

AU - Dervillez, Xavier

AU - Seguin-Devaux, Carole

AU - Cohen, Jacques H. M.

N1 - M1 - 20230130737

PY - 2023/4/27

Y1 - 2023/4/27

N2 - The present invention is situated in the field of multimers used for targeted therapies. More particularly, the invention relates to methods for preparing multifunctional heteromultimeric protein complexes with a defined ratio of functional components and to multifunctional heteromultimeric protein complexes for directing complement-dependent cytolysis, optionally comprising a scaffold, which display three or more different functional components present in a defined relative ratio, of which one is a tracking component.

AB - The present invention is situated in the field of multimers used for targeted therapies. More particularly, the invention relates to methods for preparing multifunctional heteromultimeric protein complexes with a defined ratio of functional components and to multifunctional heteromultimeric protein complexes for directing complement-dependent cytolysis, optionally comprising a scaffold, which display three or more different functional components present in a defined relative ratio, of which one is a tracking component.

KW - Protein

M3 - Patent

ER -

Multifunctional Heteromultimeric Constructs

Abstract

Keywords

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