TY - JOUR
T1 - Multi-omics Quality Assessment in Personalized Medicine Through European Infrastructure for Translational Medicine (EATRIS)
T2 - An Overview
AU - Žižkovičová, Patricia
AU - Zheng, Yuanting
AU - Yadav, Bhagwan
AU - Weiss, Janneke
AU - Valenti, Beatrice
AU - Tunstall, Tanushree
AU - Stanková, Jarmila
AU - Shi, Leming
AU - Scherer, Andreas
AU - Saracino, Sabrina
AU - Rodríguez-Serrano, Esperanza Macarena
AU - Ramos-Muñoz, Miren Edurne
AU - Quintero, Ileana
AU - Puhka, Maija
AU - Palva, Aino
AU - Övernäs, Elin
AU - Oldoni, Emanuela
AU - Nordlund, Jessica
AU - Nieminen, Anni I.
AU - Niehues, Anna
AU - Nazir, Kenneth
AU - Najdekr, Lukáš
AU - Mattila, Pirkko
AU - Martin, Tom
AU - Maestro, Roberta
AU - Liu, Yaqing
AU - Lindgren, Hanna
AU - ´t Hoen, Peter Bram
AU - Hannula, Sari
AU - Halder, Rashi
AU - Hajdúch, Marián
AU - Habier, Janine
AU - van Gool, Alain
AU - Gloerich, Jolein
AU - Ghimire, Bishwa
AU - Gasparotto, Daniela
AU - García Bermejo, Maria Laura
AU - Ekberg, Sara
AU - Džubák, Petr
AU - Donner, Kati
AU - Crespo-Toro, Lorena
AU - Conde Moreno, Elisa
AU - Chen, Qiaochu
AU - Baldazzi, Davide
AU - Alonso-Andrés, Patricia
AU - EATRIS-Plus Multi-omics working group and Stakeholders
N1 - Funding Open Access funding provided by University of Helsinki
(including Helsinki University Central Hospital). The work conducted has received funding from the European Union's Horizon 2020 research and innovation program under project EATRIS-Plus (Grant Agreement No. 871096).
Publisher Copyright:
© The Author(s) 2025.
PY - 2025/4/1
Y1 - 2025/4/1
N2 - Molecular characterization of a biological sample, e.g., with omics approaches, is fundamental for the development and implementation of personalized and precision medicine approaches. In this context, quality assessment is one of the most critical aspects. Accurate performance and interpretation of omics techniques is based on consensus, harmonization, and standardization of protocols, procedures, data analysis and reference values and materials. EATRIS, the European Infrastructure for Translational Medicine (www.EATRIS.eu), brings together resources and services to support researchers in developing their biomedical discoveries into novel translational tools and interventions for better health outcomes. Here we describe the efforts within the Horizon 2020 EATRIS-Plus project and activities of member facilities of EATRIS towards quality assessment of pre-clinical sample processing, clinical omics data generation, multi-omics data integration, and dissemination of the resources in a Multi-Omics Toolbox, which is the principal deliverable of the EATRIS-Plus project for the consolidation of EATRIS towards translational medicine.
AB - Molecular characterization of a biological sample, e.g., with omics approaches, is fundamental for the development and implementation of personalized and precision medicine approaches. In this context, quality assessment is one of the most critical aspects. Accurate performance and interpretation of omics techniques is based on consensus, harmonization, and standardization of protocols, procedures, data analysis and reference values and materials. EATRIS, the European Infrastructure for Translational Medicine (www.EATRIS.eu), brings together resources and services to support researchers in developing their biomedical discoveries into novel translational tools and interventions for better health outcomes. Here we describe the efforts within the Horizon 2020 EATRIS-Plus project and activities of member facilities of EATRIS towards quality assessment of pre-clinical sample processing, clinical omics data generation, multi-omics data integration, and dissemination of the resources in a Multi-Omics Toolbox, which is the principal deliverable of the EATRIS-Plus project for the consolidation of EATRIS towards translational medicine.
KW - European infrastructure for translational medicine
KW - Multi-omics
KW - Multi-omics toolbox
KW - Quality
KW - Reference samples
UR - http://www.scopus.com/inward/record.url?scp=105002084056&partnerID=8YFLogxK
U2 - 10.1007/s43657-024-00170-0
DO - 10.1007/s43657-024-00170-0
M3 - Review article
AN - SCOPUS:105002084056
SN - 2730-583X
JO - Phenomics
JF - Phenomics
M1 - 101177
ER -