Molecular epidemiology of chicken anemia virus (CAV) in southeastern Chinese live birds markets

M. F. Ducatez, H. Chen, Y. Guan, C. P. Muller

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Abstract

Between January 2004 and December 2005, cloacal swabs from essentially healthy chickens and silky chickens from live birds markets in Guangdong and Hunan provinces in southeastern China were screened for chicken anemia virus (CAV) by polymerase chain reaction. Phylogenetic analysis of the major structural protein VP1 sequences showed no clear genotype cluster and no correlation with the geographic origin of CAV strains. Virus evolution at the amino acid level was very slow, which corresponds to a strong negative selection of the VP1 gene in China and worldwide. A high proportion (87%) of birds was CAV positive, suggesting that many farms in the region were infected. Further investigations are necessary to evaluate the economic losses caused by CAV and the cost-benefit of vaccination.

Original languageEnglish
Pages (from-to)68-73
Number of pages6
JournalAvian Diseases
Volume52
Issue number1
DOIs
Publication statusPublished - Mar 2008

Keywords

  • Chicken anemia virus
  • China
  • Live birds markets

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