Abstract
Summary: Parkinson's disease (PD) is characterized by progressive motor and non-motor symptoms, leading to distinct diagnostic and therapeutic challenges in all stages of the disease. This study investigated a mobile biosensor-based gait analysis system for patients in early and intermediate stages of PD compared to controls. Subjects wearing a motion sensor-equipped shoe performed a standardized gait exercise. Accelerometer-and gyroscope-based signals were analysed using a complex set of pattern recognition algorithms. The analysis was able (1) to distinguish between PD patients and controls, (2) to identify patients at an early stage of the disease and (3) to distinguish between early and intermediate stage patients. Thus, using this mobile biosensor-based analysis system we were able to obtain objective classifications of gait characteristics in PD. Future studies will show that mobile biosensor-based movement detection technology will support identification of early PD stages and allow objective characterization of motor fluctuations in advanced stages of the disease. This will provide an important and supportive tool for patients, caregivers and therapists.
| Translated title of the contribution | Mobile biosensor-based gait analysis: A diagnostic and therapeutic tool in Parkinson's disease |
|---|---|
| Original language | German |
| Pages (from-to) | 1604-1611 |
| Number of pages | 8 |
| Journal | Der Nervenarzt |
| Volume | 82 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 2011 |
| Externally published | Yes |
Keywords
- Biosensor system
- Gait disorder Gait analysis
- Parkinson's disease
- Pattern recognition