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Malarial hemozoin is a Nalp3 inflammasome activating danger signal
Catherine Dostert
*
, Greta Guarda
, Jackeline F. Romero
, Philippe Menu
, Olaf Gross
, Aubry Tardivel
, Mario Luca Suva
, Jean Christophe Stehle
, Manfred Kopf
, Ivan Stamenkovic
, Giampietro Corradin
, Jurg Tschopp
*
Corresponding author for this work
Research output
:
Contribution to journal
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Article
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Research
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peer-review
330
Citations (Scopus)
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Medicine and Dentistry
Hemozoin
100%
Inflammasome
100%
Cerebral Malaria
28%
Plasmodium
28%
Neurodegeneration
14%
Erythrocyte
14%
Interleukin-1
14%
Potassium Ion
14%
Parasitemia
14%
Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase
14%
Effusion
14%
Detoxication
14%
Interleukin 1beta Converting Enzyme
14%
Plasmodium berghei
14%
Peritonitis
14%
Recurrent Fever
14%
Intraperitoneal Drug Administration
14%
Phagocytosis
14%
Heme
14%
Pharmacology, Toxicology and Pharmaceutical Science
Inflammasome
100%
Hemozoin
100%
Plasmodium
28%
Cerebral Malaria
28%
Nerve Degeneration
14%
Intraperitoneal Injection
14%
Plasmodium berghei
14%
Effusion
14%
Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase
14%
Parasitemia
14%
Potassium Ion
14%
Detoxication
14%
Sporozoite
14%
Interleukin 1beta Converting Enzyme
14%
Peritonitis
14%
Recurrent Fever
14%
Heme
14%
Immunology and Microbiology
Hemozoin
100%
Inflammasome
100%
Plasmodium
28%
Interleukin-1
14%
Phagocytosis
14%
Parasitemia
14%
Peritonitis
14%
Caspase 1
14%
Plasmodium berghei
14%
Sporozoite
14%
Heme
14%
Hemoglobin
14%
NADPH Oxidase
14%
Keyphrases
Hemozoin
100%
Cerebral Malaria
28%
Sporozoite
14%
Detoxification
14%
K+ Efflux
14%
Heme
14%
Particulate
14%
Infected Red Blood Cell
14%
Plasmodium Species
14%
Associated Pathologies
14%
Caspase-1
14%
Hemoglobin Degradation
14%
IL-1R
14%
Acute Peritonitis
14%
Recurrent Fever
14%
Background Characteristics
14%
Plasmodium Berghei
14%
Plasmodium
14%
Activating Agent
14%