Long-term reduction of wear and osteolysis with cross-linked PE? 13-year follow-up of a prospectively randomized comparison with conventional PE

Bernd Grimm*, Alphons Tonino, Ide Christiaan Heyligers

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Citations (Scopus)

Abstract

Cross-linked polyethylene (PE) for total hip arthroplasty still lacks long-term clinical evidence about its sustained performance in wear reduction and its effect on reducing osteolysis, while concerns persist about oxidation and the higher osteolytic potential of the wear debris. This 13 years follow-up of a randomized controlled trial (n48 patients) compares the first generation of a moderately cross-linked and annealed PE (Stryker Duration) to conventional, now historic PE by measuring wear as linear head penetration (Roman V 1.70) and counting osteolytic cysts on digital radiographs. Wear rates were significantly (p = 0.005) lower for Duration (0.063 ± 0.027 mm/year) than conventional PE (0.122 ± 0.065 mm/year). This reduction (-48%) compared well to the original simulator prediction (-45%) and even increased with time (-30% at 5 years, -38% at 8 years, -42% at 10 years). Acetabular cysts were less frequent in the Duration (4/13 = 31%) than in conventional group (13/18 = 72%, p = 0.023). No evidence of oxidative degradation or elevated osteolytic potential of the wear debris was found but reduced wear and less osteolysis at long follow-up.

Original languageEnglish
Title of host publicationTotal Hip Arthroplasty
Subtitle of host publicationWear Behaviour of Different Articulations
PublisherSpringer-Verlag Berlin Heidelberg
Pages59-70
Number of pages12
ISBN (Electronic)9783642356537
ISBN (Print)3642273602, 9783642356520
DOIs
Publication statusPublished - 1 Jun 2013
Externally publishedYes

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