Cross-linked polyethylene (PE) for total hip arthroplasty still lacks long-term clinical evidence about its sustained performance in wear reduction and its effect on reducing osteolysis, while concerns persist about oxidation and the higher osteolytic potential of the wear debris. This 13 years follow-up of a randomized controlled trial (n48 patients) compares the first generation of a moderately cross-linked and annealed PE (Stryker Duration) to conventional, now historic PE by measuring wear as linear head penetration (Roman V 1.70) and counting osteolytic cysts on digital radiographs. Wear rates were significantly (p = 0.005) lower for Duration (0.063 ± 0.027 mm/year) than conventional PE (0.122 ± 0.065 mm/year). This reduction (-48%) compared well to the original simulator prediction (-45%) and even increased with time (-30% at 5 years, -38% at 8 years, -42% at 10 years). Acetabular cysts were less frequent in the Duration (4/13 = 31%) than in conventional group (13/18 = 72%, p = 0.023). No evidence of oxidative degradation or elevated osteolytic potential of the wear debris was found but reduced wear and less osteolysis at long follow-up.
|Title of host publication||Total Hip Arthroplasty|
|Subtitle of host publication||Wear Behaviour of Different Articulations|
|Publisher||Springer-Verlag Berlin Heidelberg|
|Number of pages||12|
|ISBN (Print)||3642273602, 9783642356520|
|Publication status||Published - 1 Jun 2013|