Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment

P. Moreno; C. Abreu; M. Borge; F. Palacios; P. Morande; M. Pegazzano; S. Bianchi; A. I. Landoni; R. Agrelo; M. Giordano; G. Dighiero; R. Gamberale; P. Oppezzo

doi:10.1038/leu.2012.212

Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment

P. Moreno^*, C. Abreu, M. Borge, F. Palacios, P. Morande, M. Pegazzano, S. Bianchi, A. I. Landoni, R. Agrelo, M. Giordano, G. Dighiero, R. Gamberale, P. Oppezzo

^*Corresponding author for this work

Research output: Contribution to journal › Letter › peer-review

14 Citations (Scopus)

Original language	English
Pages (from-to)	721-725
Number of pages	5
Journal	Leukemia
Volume	27
Issue number	3
DOIs	https://doi.org/10.1038/leu.2012.212
Publication status	Published - Mar 2013
Externally published	Yes

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10.1038/leu.2012.212

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Moreno, P., Abreu, C., Borge, M., Palacios, F., Morande, P., Pegazzano, M., Bianchi, S., Landoni, A. I., Agrelo, R., Giordano, M., Dighiero, G., Gamberale, R., & Oppezzo, P. (2013). Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment. Leukemia, 27(3), 721-725. https://doi.org/10.1038/leu.2012.212

@article{4482c6d8b41844e3ab48b243851a8832,

title = "Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment",

author = "P. Moreno and C. Abreu and M. Borge and F. Palacios and P. Morande and M. Pegazzano and S. Bianchi and Landoni, {A. I.} and R. Agrelo and M. Giordano and G. Dighiero and R. Gamberale and P. Oppezzo",

note = "Funding Information: This work was supported by grants from CHLCC (Comisi{\'o}n Honoraria de Lucha contra el C{\'a}ncer) and ANII (Agencia Nacional de Investigaci{\'o}n e Innovaci{\'o}n), Montevideo, Uruguay. We wish to thank Gonzalo Obal, Gonzalo Moratorio and Cecilia Portela for technical assistance, Dr Otto Pritsch and Dr Miquel Llobera for critical comments, Dr J Brunzell for anti-LPL antibody and Mrs Ivana Faccini for helpful secretarial assistance. Funding Information: We thank Christopher Baum and Olga Kustikova for their help with the ligation-mediated PCR and Martin Stanulla and Martin Schrappe for the provision of sample L4951. SB is funded by a Medical Research Council (MRC) Clinical Research Training Fellowship. The IVIS Spectrum was funded by a grant from the Wellcome Trust, grant 087961. Additional funding came from Leukaemia Lymphoma Research (LLR) and core infrastructure support from the North of England Children′s Cancer Research Fund (NECCR).",

year = "2013",

month = mar,

doi = "10.1038/leu.2012.212",

language = "English",

volume = "27",

pages = "721--725",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Springer Nature",

number = "3",

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Moreno, P, Abreu, C, Borge, M, Palacios, F, Morande, P, Pegazzano, M, Bianchi, S, Landoni, AI, Agrelo, R, Giordano, M, Dighiero, G, Gamberale, R & Oppezzo, P 2013, 'Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment', Leukemia, vol. 27, no. 3, pp. 721-725. https://doi.org/10.1038/leu.2012.212

TY - JOUR

T1 - Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment

AU - Moreno, P.

AU - Abreu, C.

AU - Borge, M.

AU - Palacios, F.

AU - Morande, P.

AU - Pegazzano, M.

AU - Bianchi, S.

AU - Landoni, A. I.

AU - Agrelo, R.

AU - Giordano, M.

AU - Dighiero, G.

AU - Gamberale, R.

AU - Oppezzo, P.

N1 - Funding Information: This work was supported by grants from CHLCC (Comisión Honoraria de Lucha contra el Cáncer) and ANII (Agencia Nacional de Investigación e Innovación), Montevideo, Uruguay. We wish to thank Gonzalo Obal, Gonzalo Moratorio and Cecilia Portela for technical assistance, Dr Otto Pritsch and Dr Miquel Llobera for critical comments, Dr J Brunzell for anti-LPL antibody and Mrs Ivana Faccini for helpful secretarial assistance. Funding Information: We thank Christopher Baum and Olga Kustikova for their help with the ligation-mediated PCR and Martin Stanulla and Martin Schrappe for the provision of sample L4951. SB is funded by a Medical Research Council (MRC) Clinical Research Training Fellowship. The IVIS Spectrum was funded by a grant from the Wellcome Trust, grant 087961. Additional funding came from Leukaemia Lymphoma Research (LLR) and core infrastructure support from the North of England Children′s Cancer Research Fund (NECCR).

PY - 2013/3

Y1 - 2013/3

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U2 - 10.1038/leu.2012.212

DO - 10.1038/leu.2012.212

M3 - Letter

C2 - 22828442

AN - SCOPUS:84875223264

SN - 0887-6924

VL - 27

SP - 721

EP - 725

JO - Leukemia

JF - Leukemia

IS - 3

ER -

Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment

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