Joint antibacterial activity of soil-adsorbed antibiotics trimethoprim and sulfamethazine

Feng Jiao Peng; Guang Guo Ying; You Sheng Liu; Hao Chang Su; Liang Ying He

doi:10.1016/j.scitotenv.2014.10.117

Joint antibacterial activity of soil-adsorbed antibiotics trimethoprim and sulfamethazine

Feng Jiao Peng, Guang Guo Ying^*, You Sheng Liu, Hao Chang Su, Liang Ying He

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

25 Citations (Scopus)

Abstract

Trimethoprim (TMP) and sulfamethazine (SMZ) are two antibiotics that are often administered in combination. We investigated the sorption and desorption behaviors of TMP and SMZ individually as single solute and in combination as co-solute in three representative soils, and evaluated joint antibacterial activity of the soil-adsorbed antibiotics to a reference strain Escherichia coli ATCC 25922. Comparative sorption tests showed that co-solute sorption of TMP and SMZ was not considerably different from their single sorption. Soil-adsorbed TMP was found to effectively inhibit the growth of E. coli at environmentally relevant concentrations in all three soils, and moreover co-presence of SMZ enhanced the antibacterial effects on bacteria both in its dissolved form and soil-adsorbed form. Overall, the results from this study suggest that various soil-adsorbed antibiotic residues could play a joint influencing role in soil bacterial community activity.

Original language	English
Pages (from-to)	58-65
Number of pages	8
Journal	Science of the Total Environment
Volume	506-507
DOIs	https://doi.org/10.1016/j.scitotenv.2014.10.117
Publication status	Published - 5 Feb 2015
Externally published	Yes

Keywords

Antibacterial activity
Antibiotics
Desorption
Sorption
Sulfamethazine
Trimethoprim

Access to Document

10.1016/j.scitotenv.2014.10.117

Cite this

@article{0e1c393f3ec94937a805668d91dfc1c5,

title = "Joint antibacterial activity of soil-adsorbed antibiotics trimethoprim and sulfamethazine",

abstract = "Trimethoprim (TMP) and sulfamethazine (SMZ) are two antibiotics that are often administered in combination. We investigated the sorption and desorption behaviors of TMP and SMZ individually as single solute and in combination as co-solute in three representative soils, and evaluated joint antibacterial activity of the soil-adsorbed antibiotics to a reference strain Escherichia coli ATCC 25922. Comparative sorption tests showed that co-solute sorption of TMP and SMZ was not considerably different from their single sorption. Soil-adsorbed TMP was found to effectively inhibit the growth of E. coli at environmentally relevant concentrations in all three soils, and moreover co-presence of SMZ enhanced the antibacterial effects on bacteria both in its dissolved form and soil-adsorbed form. Overall, the results from this study suggest that various soil-adsorbed antibiotic residues could play a joint influencing role in soil bacterial community activity.",

keywords = "Antibacterial activity, Antibiotics, Desorption, Sorption, Sulfamethazine, Trimethoprim",

author = "Peng, {Feng Jiao} and Ying, {Guang Guo} and Liu, {You Sheng} and Su, {Hao Chang} and He, {Liang Ying}",

note = "Publisher Copyright: {\textcopyright} 2014 Elsevier B.V.",

year = "2015",

month = feb,

day = "5",

doi = "10.1016/j.scitotenv.2014.10.117",

language = "English",

volume = "506-507",

pages = "58--65",

journal = "Science of the Total Environment",

issn = "0048-9697",

publisher = "Elsevier",

}

TY - JOUR

T1 - Joint antibacterial activity of soil-adsorbed antibiotics trimethoprim and sulfamethazine

AU - Peng, Feng Jiao

AU - Ying, Guang Guo

AU - Liu, You Sheng

AU - Su, Hao Chang

AU - He, Liang Ying

PY - 2015/2/5

Y1 - 2015/2/5

N2 - Trimethoprim (TMP) and sulfamethazine (SMZ) are two antibiotics that are often administered in combination. We investigated the sorption and desorption behaviors of TMP and SMZ individually as single solute and in combination as co-solute in three representative soils, and evaluated joint antibacterial activity of the soil-adsorbed antibiotics to a reference strain Escherichia coli ATCC 25922. Comparative sorption tests showed that co-solute sorption of TMP and SMZ was not considerably different from their single sorption. Soil-adsorbed TMP was found to effectively inhibit the growth of E. coli at environmentally relevant concentrations in all three soils, and moreover co-presence of SMZ enhanced the antibacterial effects on bacteria both in its dissolved form and soil-adsorbed form. Overall, the results from this study suggest that various soil-adsorbed antibiotic residues could play a joint influencing role in soil bacterial community activity.

AB - Trimethoprim (TMP) and sulfamethazine (SMZ) are two antibiotics that are often administered in combination. We investigated the sorption and desorption behaviors of TMP and SMZ individually as single solute and in combination as co-solute in three representative soils, and evaluated joint antibacterial activity of the soil-adsorbed antibiotics to a reference strain Escherichia coli ATCC 25922. Comparative sorption tests showed that co-solute sorption of TMP and SMZ was not considerably different from their single sorption. Soil-adsorbed TMP was found to effectively inhibit the growth of E. coli at environmentally relevant concentrations in all three soils, and moreover co-presence of SMZ enhanced the antibacterial effects on bacteria both in its dissolved form and soil-adsorbed form. Overall, the results from this study suggest that various soil-adsorbed antibiotic residues could play a joint influencing role in soil bacterial community activity.

KW - Antibacterial activity

KW - Antibiotics

KW - Desorption

KW - Sorption

KW - Sulfamethazine

KW - Trimethoprim

UR - http://www.scopus.com/inward/record.url?scp=84909636198&partnerID=8YFLogxK

U2 - 10.1016/j.scitotenv.2014.10.117

DO - 10.1016/j.scitotenv.2014.10.117

M3 - Article

C2 - 25460939

AN - SCOPUS:84909636198

SN - 0048-9697

VL - 506-507

SP - 58

EP - 65

JO - Science of the Total Environment

JF - Science of the Total Environment

ER -

Joint antibacterial activity of soil-adsorbed antibiotics trimethoprim and sulfamethazine

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this