IS231A transposition: Conservative versus replicative pathway

C. Léonard, J. Mahillon*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)


This paper describes a novel approach, based on suicide transposition, to addressing the question of whether IS231A can give rise to cointegrate molecules through replicative transposition, even at a very low frequency. Comparative analysis was carried out with IS 10, another member of the same IS4 family. The results indicate that transposition of both elements is exclusively conservative.

Original languageEnglish
Pages (from-to)549-555
Number of pages7
JournalResearch in Microbiology
Issue number8
Publication statusPublished - Sept 1998
Externally publishedYes


  • Bacillus subtilis
  • Insertion sequence IS231A
  • Replication
  • Transposition


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