Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease

Michele Vacca; Ioannis Kamzolas; Lea Morch Harder; Fiona Oakley; Christian Trautwein; Maximilian Hatting; Trenton Ross; Barbara Bernardo; Anouk Oldenburger; Sara Toftegaard Hjuler; Iwona Ksiazek; Daniel Linden; Detlef Schuppan; Sergio Rodriguez-Cuenca; Maria Manuela Tonini; Aimo Kannt; Tamara Rodriguez-Castaneda; Cecilia M. P. Rodrigues; Simon Cockell; Olivier Govaere; Ann K. Daly; Michael Allison; Kristian Honnens De Lichtenberg; Yong Ook Kim; Anna Lindblom; Stephanie Oldham; Anne-Christine Andreasson; Franklin Schlerman; Jonathon Marioneaux; Arun Sanyal; Marta B. Afonso; Anthony Rinaldi; Yuichiro Amano; Valerie Paradis; Alastair Burt; Davies Susan; Ann Driessen; Hiroaki Yashiro; M. Julia Brosnan; Carla Yunis; Pierre Bedossa; Dina Tiniakos; Quentin Anstee; Evangelia Petsalaki; Peter Davidsen; Jim Perfield; Antonio Vidal-Puig

doi:10.1016/S0168-8278(22)00436-6

Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease

Michele Vacca
, Ioannis Kamzolas
, Lea Morch Harder
, Fiona Oakley
, Christian Trautwein
, Maximilian Hatting
, Trenton Ross
, Barbara Bernardo
, Anouk Oldenburger
, Sara Toftegaard Hjuler
, Iwona Ksiazek
, Daniel Linden
, Detlef Schuppan
, Sergio Rodriguez-Cuenca
, Maria Manuela Tonini
, Aimo Kannt
, Tamara Rodriguez-Castaneda
, Cecilia M. P. Rodrigues
, Simon Cockell
, Olivier Govaere

Ann K. Daly, Michael Allison, Kristian Honnens De Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andreasson, Franklin Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B. Afonso, Anthony Rinaldi, Yuichiro Amano, Valerie Paradis, Alastair Burt, Davies Susan, Ann Driessen, Hiroaki Yashiro, M. Julia Brosnan, Carla Yunis, Pierre Bedossa, Dina Tiniakos, Quentin Anstee, Evangelia Petsalaki, Peter Davidsen, Jim Perfield, Antonio Vidal-Puig

Clinical Research Project Management 2

Research output: Contribution to journal › Meeting Abstract › peer-review

Original language	English
Pages (from-to)	S7-S8
Journal	Journal of Hepatology
Volume	77
Issue number	Suppl.1
DOIs	https://doi.org/10.1016/S0168-8278(22)00436-6
Publication status	Published - Jul 2022
Event	International Liver Congress 2022 - London, United Kingdom Duration: 25 Jun 2022 → 26 Jun 2022

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Vacca, M., Kamzolas, I., Harder, L. M., Oakley, F., Trautwein, C., Hatting, M., Ross, T., Bernardo, B., Oldenburger, A., Hjuler, S. T., Ksiazek, I., Linden, D., Schuppan, D., Rodriguez-Cuenca, S., Tonini, M. M., Kannt, A., Rodriguez-Castaneda, T., Rodrigues, C. M. P., Cockell, S., ... Vidal-Puig, A. (2022). Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease. Journal of Hepatology, 77(Suppl.1), S7-S8. https://doi.org/10.1016/S0168-8278(22)00436-6

@article{32e63e579c8646b1870431209de8e516,

title = "Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease",

author = "Michele Vacca and Ioannis Kamzolas and Harder, \{Lea Morch\} and Fiona Oakley and Christian Trautwein and Maximilian Hatting and Trenton Ross and Barbara Bernardo and Anouk Oldenburger and Hjuler, \{Sara Toftegaard\} and Iwona Ksiazek and Daniel Linden and Detlef Schuppan and Sergio Rodriguez-Cuenca and Tonini, \{Maria Manuela\} and Aimo Kannt and Tamara Rodriguez-Castaneda and Rodrigues, \{Cecilia M. P.\} and Simon Cockell and Olivier Govaere and Daly, \{Ann K.\} and Michael Allison and \{De Lichtenberg\}, \{Kristian Honnens\} and Kim, \{Yong Ook\} and Anna Lindblom and Stephanie Oldham and Anne-Christine Andreasson and Franklin Schlerman and Jonathon Marioneaux and Arun Sanyal and Afonso, \{Marta B.\} and Anthony Rinaldi and Yuichiro Amano and Valerie Paradis and Alastair Burt and Davies Susan and Ann Driessen and Hiroaki Yashiro and Brosnan, \{M. Julia\} and Carla Yunis and Pierre Bedossa and Dina Tiniakos and Quentin Anstee and Evangelia Petsalaki and Peter Davidsen and Jim Perfield and Antonio Vidal-Puig",

note = "Publication of this Abstract supplement was supported by the European Association for the Study of the Liver (EASL) Funding Funded by EU Horizon 2020 IMI2 and EFPIA, Grant Agreement 777377 (LITMUS).; International Liver Congress 2022 ; Conference date: 25-06-2022 Through 26-06-2022",

year = "2022",

month = jul,

doi = "10.1016/S0168-8278(22)00436-6",

language = "English",

volume = "77",

pages = "S7--S8",

journal = "Journal of Hepatology",

issn = "0168-8278",

publisher = "Elsevier B.V.",

number = "Suppl.1",

}

Vacca, M, Kamzolas, I, Harder, LM, Oakley, F, Trautwein, C, Hatting, M, Ross, T, Bernardo, B, Oldenburger, A, Hjuler, ST, Ksiazek, I, Linden, D, Schuppan, D, Rodriguez-Cuenca, S, Tonini, MM, Kannt, A, Rodriguez-Castaneda, T, Rodrigues, CMP, Cockell, S, Govaere, O, Daly, AK, Allison, M, De Lichtenberg, KH, Kim, YO, Lindblom, A, Oldham, S, Andreasson, A-C, Schlerman, F, Marioneaux, J, Sanyal, A, Afonso, MB, Rinaldi, A, Amano, Y, Paradis, V, Burt, A, Susan, D, Driessen, A, Yashiro, H, Brosnan, MJ, Yunis, C, Bedossa, P, Tiniakos, D, Anstee, Q, Petsalaki, E, Davidsen, P, Perfield, J & Vidal-Puig, A 2022, 'Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease', Journal of Hepatology, vol. 77, no. Suppl.1, pp. S7-S8. https://doi.org/10.1016/S0168-8278(22)00436-6

TY - JOUR

T1 - Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease

AU - Vacca, Michele

AU - Kamzolas, Ioannis

AU - Harder, Lea Morch

AU - Oakley, Fiona

AU - Trautwein, Christian

AU - Hatting, Maximilian

AU - Ross, Trenton

AU - Bernardo, Barbara

AU - Oldenburger, Anouk

AU - Hjuler, Sara Toftegaard

AU - Ksiazek, Iwona

AU - Linden, Daniel

AU - Schuppan, Detlef

AU - Rodriguez-Cuenca, Sergio

AU - Tonini, Maria Manuela

AU - Kannt, Aimo

AU - Rodriguez-Castaneda, Tamara

AU - Rodrigues, Cecilia M. P.

AU - Cockell, Simon

AU - Govaere, Olivier

AU - Daly, Ann K.

AU - Allison, Michael

AU - De Lichtenberg, Kristian Honnens

AU - Kim, Yong Ook

AU - Lindblom, Anna

AU - Oldham, Stephanie

AU - Andreasson, Anne-Christine

AU - Schlerman, Franklin

AU - Marioneaux, Jonathon

AU - Sanyal, Arun

AU - Afonso, Marta B.

AU - Rinaldi, Anthony

AU - Amano, Yuichiro

AU - Paradis, Valerie

AU - Burt, Alastair

AU - Susan, Davies

AU - Driessen, Ann

AU - Yashiro, Hiroaki

AU - Brosnan, M. Julia

AU - Yunis, Carla

AU - Bedossa, Pierre

AU - Tiniakos, Dina

AU - Anstee, Quentin

AU - Petsalaki, Evangelia

AU - Davidsen, Peter

AU - Perfield, Jim

AU - Vidal-Puig, Antonio

N1 - Publication of this Abstract supplement was supported by the European Association for the Study of the Liver (EASL) Funding Funded by EU Horizon 2020 IMI2 and EFPIA, Grant Agreement 777377 (LITMUS).

PY - 2022/7

Y1 - 2022/7

U2 - 10.1016/S0168-8278(22)00436-6

DO - 10.1016/S0168-8278(22)00436-6

M3 - Meeting Abstract

SN - 0168-8278

VL - 77

SP - S7-S8

JO - Journal of Hepatology

JF - Journal of Hepatology

IS - Suppl.1

T2 - International Liver Congress 2022

Y2 - 25 June 2022 through 26 June 2022

ER -