Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL

Anne Largeot, Vanessa Klapp, Elodie Viry, Susanne Gonder, Iria Fernandez Botana, Arnaud Blomme, Mohaned Benzarti*, Sandrine Pierson, Chloé Duculty, Petra Marttila, Marina Wierz, Ernesto Gargiulo, Giulia Pagano, Ning An, Najla El Hachem, Daniel Perez Hernandez, Supriya Chakraborty, Loïc Ysebaert, Jean Hugues François, Susan Cortez ClementeGuy Berchem, Dimitar G. Efremov, Gunnar Dittmar, Martyna Szpakowska, Andy Chevigné, Petr V. Nazarov, Thomas Helleday, Pierre Close, Johannes Meiser, Basile Stamatopoulos, Laurent Désaubry, Jérôme Paggetti* (Main author), Etienne Moussay (Main author)

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology