Individual response to treatment: Is it a valid assumption?

Stephen Senn*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

113 Citations (Scopus)


Most drug trials assume that patients respond consistently to treatment, but the assumption is rarely tested. If patients vary randomly in their response to a drug rather than some patients never responding, searches for a genetic basis for non-response are futile.

Original languageEnglish
Pages (from-to)966
Number of pages1
JournalThe BMJ
Issue number7472
Publication statusPublished - 23 Oct 2004
Externally publishedYes


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