Immunological fingerprinting method for differentiation of serum samples in research-oriented biobanks

Katy Beaumont, Fotini Betsou*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

An immunoenzymatic serum fingerprinting method was developed to establish a serum sample fingerprint based on IgG titers obtained with three different antigens. Three widely expressed antigens were selected for their capacity to induce long-lasting humoral immune responses. This fingerprinting method may be used to differentiate between two serum samples and to determine whether they come from the same primary blood specimen. The method showed a specificity of 99.5%. This method is suitable as a quality control method for biobanked serum samples.

Original languageEnglish
Pages (from-to)735-740
Number of pages6
JournalClinical and Vaccine Immunology
Volume17
Issue number5
DOIs
Publication statusPublished - May 2010

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