Identifying GDF-15 as potential novel immunotherapeutic target linked to immune cell exclusion in tumors and resistance to anti-PD-1 treatment

Jorg Wischhusen; Kilian Wistuba-Hamprecht; Patrick N. Harter; Phil Cheng; Alexander Martens; Falk Gogolla; Yumi Nonomura; Paula Romer; Sven D. Koch; Markus Haake; Christine Schuberth-Wagner; Manfred Rudiger; Eugen Leo; Michael Mittelbronn; Mitchell P. Levesque; Hubert Hackl; Reinhard Dummer; Benjamin Weide

doi:10.1158/1538-7445.AM2020-2161

Identifying GDF-15 as potential novel immunotherapeutic target linked to immune cell exclusion in tumors and resistance to anti-PD-1 treatment

Jorg Wischhusen, Kilian Wistuba-Hamprecht, Patrick N. Harter, Phil Cheng, Alexander Martens, Falk Gogolla, Yumi Nonomura, Paula Romer, Sven D. Koch, Markus Haake, Christine Schuberth-Wagner, Manfred Rudiger, Eugen Leo, Michael Mittelbronn, Mitchell P. Levesque, Hubert Hackl, Reinhard Dummer, Benjamin Weide

Luxembourg Center of Neuropathology

Research output: Contribution to journal › Meeting Abstract › peer-review

Original language	English
Article number	2161
Journal	Cancer Research
Volume	80
Issue number	16 Suppl.
DOIs	https://doi.org/10.1158/1538-7445.AM2020-2161
Publication status	Published - Aug 2020
Event	Annual Meeting of the American Association for Cancer Research (AACR) 2020 - Philadelphia, United States Duration: 22 Jun 2020 → 24 Jun 2020

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10.1158/1538-7445.AM2020-2161

Cite this

Wischhusen, J., Wistuba-Hamprecht, K., Harter, P. N., Cheng, P., Martens, A., Gogolla, F., Nonomura, Y., Romer, P., Koch, S. D., Haake, M., Schuberth-Wagner, C., Rudiger, M., Leo, E., Mittelbronn, M., Levesque, M. P., Hackl, H., Dummer, R., & Weide, B. (2020). Identifying GDF-15 as potential novel immunotherapeutic target linked to immune cell exclusion in tumors and resistance to anti-PD-1 treatment. Cancer Research, 80(16 Suppl.), Article 2161. https://doi.org/10.1158/1538-7445.AM2020-2161

@article{7393565548564e99b9c8d52d264c4d1b,

title = "Identifying GDF-15 as potential novel immunotherapeutic target linked to immune cell exclusion in tumors and resistance to anti-PD-1 treatment",

author = "Jorg Wischhusen and Kilian Wistuba-Hamprecht and Harter, {Patrick N.} and Phil Cheng and Alexander Martens and Falk Gogolla and Yumi Nonomura and Paula Romer and Koch, {Sven D.} and Markus Haake and Christine Schuberth-Wagner and Manfred Rudiger and Eugen Leo and Michael Mittelbronn and Levesque, {Mitchell P.} and Hubert Hackl and Reinhard Dummer and Benjamin Weide",

year = "2020",

month = aug,

doi = "10.1158/1538-7445.AM2020-2161",

language = "English",

volume = "80",

journal = "Cancer Research",

issn = "0008-5472",

publisher = "American Association for Cancer Research Inc.",

number = "16 Suppl.",

note = "Annual Meeting of the American Association for Cancer Research (AACR) 2020 ; Conference date: 22-06-2020 Through 24-06-2020",

}

Wischhusen, J, Wistuba-Hamprecht, K, Harter, PN, Cheng, P, Martens, A, Gogolla, F, Nonomura, Y, Romer, P, Koch, SD, Haake, M, Schuberth-Wagner, C, Rudiger, M, Leo, E, Mittelbronn, M, Levesque, MP, Hackl, H, Dummer, R & Weide, B 2020, 'Identifying GDF-15 as potential novel immunotherapeutic target linked to immune cell exclusion in tumors and resistance to anti-PD-1 treatment', Cancer Research, vol. 80, no. 16 Suppl., 2161. https://doi.org/10.1158/1538-7445.AM2020-2161

TY - JOUR

T1 - Identifying GDF-15 as potential novel immunotherapeutic target linked to immune cell exclusion in tumors and resistance to anti-PD-1 treatment

AU - Wischhusen, Jorg

AU - Wistuba-Hamprecht, Kilian

AU - Harter, Patrick N.

AU - Cheng, Phil

AU - Martens, Alexander

AU - Gogolla, Falk

AU - Nonomura, Yumi

AU - Romer, Paula

AU - Koch, Sven D.

AU - Haake, Markus

AU - Schuberth-Wagner, Christine

AU - Rudiger, Manfred

AU - Leo, Eugen

AU - Mittelbronn, Michael

AU - Levesque, Mitchell P.

AU - Hackl, Hubert

AU - Dummer, Reinhard

AU - Weide, Benjamin

PY - 2020/8

Y1 - 2020/8

U2 - 10.1158/1538-7445.AM2020-2161

DO - 10.1158/1538-7445.AM2020-2161

M3 - Meeting Abstract

SN - 0008-5472

VL - 80

JO - Cancer Research

JF - Cancer Research

IS - 16 Suppl.

M1 - 2161

T2 - Annual Meeting of the American Association for Cancer Research (AACR) 2020

Y2 - 22 June 2020 through 24 June 2020

ER -