Identification of human parvovirus B19 among measles and rubella suspected patients from Cuba

María de los Ángeles Ribas*, Yahisel Tejero, Yanislet Cordero, Daileny Pérez, Aurélie Sausy, Claude P. Muller, Judith M. Hübschen

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Abstract

Between September 2014 and December 2015, 298 sera from rash and fever patients from all over Cuba were investigated for specific IgM antibodies against measles, rubella, dengue, human parvovirus B19 (B19V) and human herpesvirus 6 (HHV6) using a commercial enzyme-linked immunosorbent assay kits. B19V IgM positive and equivocal samples were investigated by a polymerase chain reaction and genotyping. No measles, rubella or dengue cases were detected. HHV6-IgM antibodies were confirmed in 5.7% and B19V-IgM antibodies in 10.7% of the patients. A total of 31.3% of the B19V cases were between 5 and 9 years old and 34.4% were 20 years and older. The only B19V sequence obtained belonged to genotype 1a. Diagnosis was established for only 16% of the rash and fever patients, suggesting that other diseases such as Zika or Chikungunya may play a role.

Original languageEnglish
Pages (from-to)1351-1354
Number of pages4
JournalJournal of Medical Virology
Volume91
Issue number7
DOIs
Publication statusPublished - Jul 2019

Keywords

  • Cuba
  • human parvovirus B19
  • rash-fever

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