Identification of DNA damage response genes as targets for personalized treatment of Glioblastoma through RNA interference screens

Medicine and Dentistry

• Glioblastoma 100%
• DNA Damage Response 100%
• Temozolomide 100%
• DNA Methyltransferase 100%
• 6 O Methylguanine 100%
• RNAI 100%
• DNA Repair 30%
• Neoplasm 20%
• Short Hairpin RNA 20%
• Base Excision Repair 20%
• Malignant Neoplasm 10%
• Cell Survival 10%
• In Vitro 10%
• Chemotherapy 10%
• Alkylating Antineoplastic Agent 10%
• Ionizing Radiation 10%
• Promoter Region 10%
• Glioblastoma Cell Line 10%
• Predictive Marker 10%
• Surgery 10%
• Methylation 10%
• Drug Resistance 10%
• Cell Line 10%
• Combination Drug 10%

Biochemistry, Genetics and Molecular Biology

• DNA Damage Response 100%
• O-6-Methylguanine-DNA Methyltransferase 100%
• RNAI 100%
• DNA Repair 30%
• Transcription 20%
• Nucleotide Excision Repair 20%
• Small Hairpin RNA 20%
• Base Excision Repair 20%
• Response Factor 20%
• Epigenetics 10%
• Methylation 10%
• Cell Survival 10%
• Promoter Region 10%
• Drug Resistance 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Glioblastoma 100%
• Temozolomide 90%
• DNA Methyltransferase 90%
• 6 O Methylguanine 90%
• Neoplasm 18%
• Short Hairpin RNA 18%
• Chemotherapy 9%
• Ionizing Radiation 9%
• Malignant Neoplasm 9%
• Alkylating Agent 9%
• Combination Drug 9%
• Drug Resistance 9%