Hydrogel embedded oligodoxynucleotides as tolerognic adjuvant for subcutaneous immunotherapy

Reinhard Bredehorst (Inventor), Thomas Grunwald (Inventor), Cathy Léonard (Inventor), Markus Ollert (Inventor)

Research output: Patent

Abstract

The present invention discloses novel hydrogel-based technologies and methods for subcutaneous immunotherapy of allergic and autoimmune diseases which allows tolerogenic modulation of human antigen-presenting cells (APCs) including dendritic cells and macrophages with CpG-ODN or GpC-ODN or GpB-ODN at tolerted dose levels.
Original languageEnglish
IPCWO 2019/076478
Publication statusPublished - 24 Apr 2019

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