Holocord pilocytic astrocytoma-Case report and review of the literature

Jens Schittenhelm*, Florian H. Ebner, Marcos Tatagiba, Markus Wolff, Thomas Nägele, Richard Meyermann, Michel Mittelbronn

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Abstract

Intramedullary glial neoplasms affecting the entire cord from the cervicomedullary junction to the conus are termed "holocord tumors" and those diagnosed as pilocytic astrocytoma are rare. Herein, we present a 13-year-old girl with a tumor extending from the cervicomedullary junction to the conus which was partially resected in a four-stage approach. Histopathological examination of all specimens resulted in diagnosis of a pilocytic astrocytoma. Although no signs of atypia were present, an elevated proliferative activity of endothelial vessels was noted. Residual parts of the tumor showed progress making additional surgery necessary. Therapy and its consequences are discussed and an overview of the literature of these rare longitudinally extensive intramedullary lesions is given.

Original languageEnglish
Pages (from-to)203-207
Number of pages5
JournalClinical Neurology and Neurosurgery
Volume111
Issue number2
DOIs
Publication statusPublished - Feb 2009
Externally publishedYes

Keywords

  • Intramedullary astrocytoma
  • Pilocytic astrocytoma
  • Spinal cord tumor

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