TY - JOUR
T1 - High genetic diversity of measles virus, World Health Organization European Region, 2005-2006
AU - Kremer, Jacques R.
AU - Brown, Kevin E.
AU - Jin, Li
AU - Santibanez, Sabine
AU - Shulga, Sergey V.
AU - Aboudy, Yair
AU - Demchyshyna, Irina V.
AU - Djemileva, Sultana
AU - Echevarria, Juan E.
AU - Featherstone, David F.
AU - Hukic, Mirsada
AU - Johansen, Kari
AU - Litwinska, Bogumila
AU - Lopareva, Elena
AU - Lupulescu, Emilia
AU - Mentis, Andreas
AU - Mihneva, Zefira
AU - Mosquera, Maria M.
AU - Muscat, Mark
AU - Naumova, M. A.
AU - Nedeljkovic, Jasminka
AU - Nekrasova, Ljubov S.
AU - Magurano, Fabio
AU - Fortuna, Claudia
AU - De Andrade, Helena Rebelo
AU - Richard, Jean Luc
AU - Robo, Alma
AU - Rota, Paul A.
AU - Samoilovich, Elena O.
AU - Sarv, Inna
AU - Semeiko, Galina V.
AU - Shugayev, Nazim
AU - Utegenova, Elmira S.
AU - Van Binnendijk, Rob
AU - Vinner, Lasse
AU - Waku-Kouomou, Diane
AU - Wild, T. Fabian
AU - Brown, David W.G.
AU - Mankertz, Annette
AU - Muller, Claude P.
AU - Mulders, Mick N.
PY - 2008/1
Y1 - 2008/1
N2 - During 2005-2006, nine measles virus (MV) genotypes were identified throughout the World Health Organization European Region. All major epidemics were associated with genotypes D4, D6, and B3. Other genotypes (B2, D5, D8, D9, G2, and H1) were only found in limited numbers of cases after importation from other continents. The genetic diversity of endemic D6 strains was low; genotypes C2 and D7, circulating in Europe until recent years, were no longer identified. The transmission chains of several indigenous MV strains may thus have been interrupted by enhanced vaccination. However, multiple importations from Africa and Asia and virus introduction into highly mobile and unvaccinated communities caused a massive spread of D4 and B3 strains throughout much of the region. Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities.
AB - During 2005-2006, nine measles virus (MV) genotypes were identified throughout the World Health Organization European Region. All major epidemics were associated with genotypes D4, D6, and B3. Other genotypes (B2, D5, D8, D9, G2, and H1) were only found in limited numbers of cases after importation from other continents. The genetic diversity of endemic D6 strains was low; genotypes C2 and D7, circulating in Europe until recent years, were no longer identified. The transmission chains of several indigenous MV strains may thus have been interrupted by enhanced vaccination. However, multiple importations from Africa and Asia and virus introduction into highly mobile and unvaccinated communities caused a massive spread of D4 and B3 strains throughout much of the region. Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities.
UR - http://www.scopus.com/inward/record.url?scp=38049028262&partnerID=8YFLogxK
UR - https://pubmed.ncbi.nlm.nih.gov/18258089
U2 - 10.3201/eid1401.070778
DO - 10.3201/eid1401.070778
M3 - Article
C2 - 18258089
AN - SCOPUS:38049028262
SN - 1080-6040
VL - 14
SP - 107
EP - 114
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 1
ER -