High genetic diversity including potential new subtypes of hepatitis C virus genotype 6 in Lao People's Democratic Republic

J. M. Hübschen, P. Jutavijittum, T. Thammavong, B. Samountry, A. Yousukh, K. Toriyama, A. Sausy, C. P. Muller*

*Corresponding author for this work

Research output: Contribution to journalComment/debate

31 Citations (Scopus)

Abstract

Sera from 105 anti-HCV-positive first-time blood donors collected in 2004, 2005 and 2008 in different provinces in Laos were investigated by PCR. Forty-five samples were positive for HCV (42.86%); two belonged to subtype 1b (2/45, 4.4%) and all others to genotype 6 (43/45, 95.6%), including subtypes 6b, 6h, 6k, 6l, 6n and 6q. Three groups of sequences were not clearly attributable to any genotype 6 subtype, two of which may be regarded as candidates for new subtypes of genotype 6. Two samples were mixed infected with different subtypes or clusters of genotype 6 viruses.

Original languageEnglish
Pages (from-to)E30-E34
JournalClinical Microbiology and Infection
Volume17
Issue number12
DOIs
Publication statusPublished - Dec 2011

Keywords

  • Genotype
  • HCV
  • Laos
  • Phylogeny
  • Subtype

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