Hans van houwelingen and the art of summing up

Stephen Senn

doi:10.1002/bimj.200900074

Hans van houwelingen and the art of summing up

Stephen Senn^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

47 Citations (Scopus)

Abstract

Some personal remarks about Hans van Houwelingen's approach to biostatistics in general are followed by a discussion of his article with Koos Zwinderman and Theo Stijnen outlining a bivariate approach to meta-analysis. It is concluded that this is more radical than many may realise in that it permits inter-trial information to be recovered. This has some advantages but in theory opens the door to bias. It is concluded that in practice the size of this bias is likely to be small. I end with some further personal remarks to Hans.

Original language	English
Pages (from-to)	85-94
Number of pages	10
Journal	Biometrical Journal
Volume	52
Issue number	1
DOIs	https://doi.org/10.1002/bimj.200900074
Publication status	Published - Feb 2010
Externally published	Yes

Keywords

Bias
Bivariate model
Inter-trial information
Meta-analysis
Random effects

Access to Document

10.1002/bimj.200900074

Cite this

@article{d4b6430572b64bf8a3e53167d4526db3,

title = "Hans van houwelingen and the art of summing up",

abstract = "Some personal remarks about Hans van Houwelingen's approach to biostatistics in general are followed by a discussion of his article with Koos Zwinderman and Theo Stijnen outlining a bivariate approach to meta-analysis. It is concluded that this is more radical than many may realise in that it permits inter-trial information to be recovered. This has some advantages but in theory opens the door to bias. It is concluded that in practice the size of this bias is likely to be small. I end with some further personal remarks to Hans.",

keywords = "Bias, Bivariate model, Inter-trial information, Meta-analysis, Random effects",

author = "Stephen Senn",

year = "2010",

month = feb,

doi = "10.1002/bimj.200900074",

language = "English",

volume = "52",

pages = "85--94",

journal = "Biometrical Journal",

issn = "0323-3847",

publisher = "Wiley-VCH Verlag",

number = "1",

}

TY - JOUR

T1 - Hans van houwelingen and the art of summing up

AU - Senn, Stephen

PY - 2010/2

Y1 - 2010/2

N2 - Some personal remarks about Hans van Houwelingen's approach to biostatistics in general are followed by a discussion of his article with Koos Zwinderman and Theo Stijnen outlining a bivariate approach to meta-analysis. It is concluded that this is more radical than many may realise in that it permits inter-trial information to be recovered. This has some advantages but in theory opens the door to bias. It is concluded that in practice the size of this bias is likely to be small. I end with some further personal remarks to Hans.

AB - Some personal remarks about Hans van Houwelingen's approach to biostatistics in general are followed by a discussion of his article with Koos Zwinderman and Theo Stijnen outlining a bivariate approach to meta-analysis. It is concluded that this is more radical than many may realise in that it permits inter-trial information to be recovered. This has some advantages but in theory opens the door to bias. It is concluded that in practice the size of this bias is likely to be small. I end with some further personal remarks to Hans.

KW - Bias

KW - Bivariate model

KW - Inter-trial information

KW - Meta-analysis

KW - Random effects

UR - http://www.scopus.com/inward/record.url?scp=77952577480&partnerID=8YFLogxK

U2 - 10.1002/bimj.200900074

DO - 10.1002/bimj.200900074

M3 - Article

C2 - 20140900

AN - SCOPUS:77952577480

SN - 0323-3847

VL - 52

SP - 85

EP - 94

JO - Biometrical Journal

JF - Biometrical Journal

IS - 1

ER -

Hans van houwelingen and the art of summing up

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this